Melarithm, 3 mg 24 pcs

It is a synthetic analogue of the pineal gland hormone (epiphysis). It normalizes circadian rhythms. It regulates sleep-wake cycle, daily changes of locomotor activity and body temperature.

It helps to normalize night sleep (accelerates falling asleep, improves the quality of sleep, reduces the number of night awakenings, improves well-being upon awakening without a feeling of dullness, weariness and tiredness upon awakening; dreams become more vivid and emotionally rich).

The body adapts to rapid changes in time zones, reduces stress reactions.

It has immune-stimulating and strong antioxidant properties.

Inhibits secretion of gonadotropins and, to a lesser extent, other adenohypophysis hormones: corticotropin, thyrotropin and somatotropin.

It is not addictive or dependent.

Pharmacokinetics

In oral administration, it is quickly and completely adsorbed and easily passes the histohematic barriers, including the blood-brain barrier. It has a short half-life.

Indications

As a sleeping aid.

As an adaptogen to normalize biological rhythms.

Active ingredient

Composition

Melatonin – 3 mg.

Additional Ingredients:

microcrystalline cellulose – 82.4 mg,

croscarmellose sodium (sodium starch glycolate) – 10.5 mg,

calcium hydrophosphate dihydrate – 82.4 mg,

mannitol – 44 mg,

macrogol 6000 (polyethylene glycol 6000) – 15 mg,

magnesium stearate – 2.7 mg.

Shell composition:

Opadray II (polyvinyl alcohol – 2.4 mg, titanium dioxide – 1.5 mg, macrogol – 1.212 mg, talc – 0.888 mg).

How to take, the dosage

Ingestion. Adults take 1.5-3 mg 30-40 minutes before going to bed once a day.

As an adaptogen when changing time zones: 1 day before the flight and 3 mg 30-40 minutes before sleep for the next 2-5 days.

The maximum daily dose is up to 6 mg per day.

Interaction

Melatonin enhances the effect of central nervous system depressants and beta-adrenoblockers.

It is not recommended to take melatonin together with hormonal drugs.

Melatonin is incompatible with monoamine oxidase inhibitors (MAOIs), glucocorticosteroids and cyclosporine.

Special Instructions

When using the drug, it is recommended to avoid exposure to bright light.

Women who want to get pregnant should be informed about the weak contraceptive effect of the drug.

Influence on driving and operating ability

At the time of treatment, it is necessary to refrain from driving and engaging in potentially dangerous activities requiring increased concentration and quick psychomotor reactions.

Contraindications

Hypersensitivity, marked renal dysfunction, autoimmune diseases, leukemia, lymphoma, allergic reactions, lymphogranulematosis, myeloma, epilepsy, diabetes, chronic renal failure, pregnancy and breast-feeding period.

Side effects

From the immune system:allergic reactions.

From the central nervous system:headache, morning drowsiness.

From the digestive system:nausea, vomiting, diarrhea.

Other:edema in the first week of administration.

Overdose

Symptoms.The severity of side effects increases.

Treatment. Gastric lavage, symptomatic therapy.

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