Melarena, 3 mg 30 pcs
€12.45 €10.38
Synthetic analogue of the pineal body hormone (epiphysis) melatonin; has adaptogenic, sedative, and hypnotic effects. It normalizes circadian rhythms.
Increases the concentration of gamma-aminobutyric acid (GABA) and serotonin in the midbrain and hypothalamus, changes the activity of pyridoxal kinase, involved in the synthesis of GABA, dopamine and serotonin.
Regulates the sleep-wake cycle, daily changes in locomotor activity and body temperature, has a positive effect on the intellectual and mental functions of the brain, on the emotional and personality sphere.
It promotes the organization of the biological rhythm and the normalization of night sleep.
It improves the quality of sleep, accelerates falling asleep, reduces the number of night awakenings, improves the sense of well-being after the morning awakening, does not cause the feeling of dullness, weariness and fatigue upon awakening.
Makes dreams more vivid and emotionally charged.
Adapts the body to rapid change of time zones, reduces stress reactions, regulates neuroendocrine functions.
Adapts the body of people sensitive to changes in weather conditions. It shows immune-stimulating and antioxidant properties.
Inhibits secretion of gonadotropins, to a lesser extent – other adenohypophysis hormones (corticotropin, thyroid hormone, somatotropic hormone). It is not addictive and not dependent.
When administered orally it is quickly and completely absorbed, easily passes through histohematic barriers including the blood-brain barrier. It has a short half-life.
Indications
Meteosensitivity, Irritability, Depression, Insomnia, Change of time zones, Weakness and fatigue
- Desynchronosis (violation of the normal circadian rhythm) due to rapid movement between the time zones of the Earth; in violation of the light regime, including in people engaged in shift work or shift work.
- Sleep disorders.
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Active ingredient
Melatonin
Composition
1 film-coated tablet contains:
The active ingredient
Melatonin – 0.30 mg or 3.00 mg;
Associates:
Calcium hydrophosphate dihydrate – 67.37/ 64.67 mg
Microcrystalline cellulose – 25.00/ 25.00 mg
Croscarmellose sodium – 2.00/ 2.00 mg
Povidone-K25 – 3,33/ 3,33 mg
Colloidal silica – 0,50/ 0,50 mg,
Talcum powder – 1,00/ 1,00 mg,
Calcium stearate – 0,50/ 0,50 mg;
Shell:
For 0.3 mg dosage (hypromellose 62.50%, triethylcitrate 12.50%, titanium dioxide 25.00%) – 3.00 mg;
For 3 mg dosage (hypromellose 62.50%, macrogoal-400 12.50%, titanium dioxide 24.21%, aluminum lacquer FD&C blue #2 (12-14%) 0.28%, aluminum varnish FD&C blue #1 (11-13%) 0.48%, quinoline yellow varnish 0.02%, iron oxide black dye 0.01%) 3.00 mg.
How to take, the dosage
In case of sleep disorders, desynchronosis – 1 tablet once a day 30-40 minutes before bedtime.
When used as an adaptogen when changing time zones – 1 day before the flight and the next 2-5 days – 1 tablet 30-40 minutes before bedtime.
Maximum daily dose – 6 mg.
Interaction
Incompatible with monoamine oxidase inhibitors (MAOIs), glucocorticosteroids, cyclosporine.
Increases the effect of drugs that depress the central nervous system and beta-adrenoblockers.
It is not recommended to take simultaneously with nonsteroidal anti-inflammatory drugs (NSAIDs).
It is not recommended to take together with hormonal drugs.
Special Instructions
During the use of the drug Melaren® it is recommended to avoid staying in bright light.
Women who want to get pregnant should be informed about the weak contraceptive effect of the drug.
Influence on the ability to drive vehicles and mechanisms
During the treatment it is necessary to be careful while driving vehicles and performing other potentially dangerous activities that require high concentration and quick psychomotor reactions.
Contraindications
Hypersensitivity to melatonin and other drug components; autoimmune diseases, allergic diseases; lymphogranulematosis, leukemia, lymphoma, myeloma, epilepsy, diabetes, chronic renal insufficiency; severe renal failure (for 3 mg dosage); pregnancy, breast-feeding; age under 18 years (effectiveness and safety of use are unknown).
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Side effects
Allergic reactions to components of the drug, headache, nausea, vomiting, diarrhea, morning drowsiness, edema (usually in the first week of use) are possible.
Overdose
There are no data on cases of melatonin overdose.
Possible increase in dose-dependent adverse reactions.
Treatment: gastric lavage, symptomatic therapy.
Similarities
Melaxen, Sonnovan, Melarena, Melatonin, Wellson, Strengthen Your Immunity by Evalar
Weight | 0.014 kg |
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Shelf life | 2 years. Do not use the drug after the expiration date stated on the package. |
Conditions of storage | In a dry, dark place at a temperature no higher than 25 ° C. Keep out of reach of children. |
Manufacturer | Chemopharm LLC, Russia |
Medication form | pills |
Brand | Chemopharm LLC |
Other forms…
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