The drug is an endogenous antioxidant that binds free radicals. Thioctic acid (α-lipoic acid) is involved in the mitochondrial metabolism of the cell, it acts as a coenzyme in the complex transformation of substances that have a pronounced antitoxic effect. They protect the cell from reactive radicals arising from intermediate metabolism or from the decay of exogenous foreign substances, and from heavy metals. Thioctic acid shows synergism with respect to insulin, which is associated with increased glucose utilization. In patients with diabetes thioctic acid leads to a change in the concentration of pyruvic acid in the blood.
Indications
Liver cirrhosis, Liver damage, Type 1 diabetes, Poisoning, Atherosclerosis, Type 2 diabetes, Polyneuropathy, AlcoholismDiabetic polyneuropathy.
Active ingredient
Thioctic acid
Composition
1 ml contains thioctoic (α-lipoic) acid – 25 mg
How to take, the dosage
A single dose is 600 mg when taken orally.
Intravenously (slowly or by trickle) administer 300-600 mg/day.
Special Instructions
Concomitant use may increase the hypoglycemic effect of insulin and oral hypoglycemic agents.
Concomitant use with cisplatin may decrease its effectiveness.
.
Contraindications
Pregnancy, lactation (breast-feeding), hypersensitivity to thioctic acid.
Side effects
After intravenous administration diplopia, seizures, petechial haemorrhages in mucous membranes and skin, impaired platelet function; when administered rapidly – increased intracranial pressure.
In oral administration dyspeptic phenomena (including nausea, vomiting, heartburn) are possible.
When administered orally or intravenously, allergic reactions (urticaria, anaphylactic shock); hypoglycemia.
.
Similarities
Berlithione 300, Berlithione 300 oral, Thioctacid BV, Tiogamma, Thiolepta, Octolipen, Berlithione, Thioctic acid
Weight | 0.140 kg |
---|---|
Manufacturer | PharmFirm Sotex, Russia |
Medication form | concentrate for preparation of infusion solution |
Brand | PharmFirm Sotex |
Related products
Buy Lipotyoxone, 25 mg/ml concentrate 12 ml 5 pcs with delivery to USA, UK, Europe and over 120 other countries.