Levomycetin, eye drops 0.25% 10 ml
€5.36 €4.08
Levomycetin is a broad spectrum antibiotic; effective against many Gram-positive cocci (gonococci and meningococci), various bacteria (E. coli and Haemophilus influenzae, Salmonella, Shigella, Klebsiella, Serreria, Yersenia, Proteus), rickettsia, spirochetes and some major viruses. The drug is active against strains resistant to penicillin, streptomycin, sulfonamides. It is weakly active against acid-resistant bacteria, Pseudomonas aeruginosa, clostridium and protozoa.
It acts bacteriostatically. The mechanism of antibacterial action is connected with disruption of protein synthesis in microorganisms.
Drug resistance to the drug develops relatively slowly, and, as a rule, cross-resistance to other chemotherapeutic agents does not occur.
Indications
Prevention and treatment of infectious eye diseases:
conjunctivitis;
blepharitis;
keratitis.
Pharmacological effect
Levomycetin is a broad-spectrum antibiotic; effective against many gram-positive cocci (gonococci and meningococci), various bacteria (Escherichia coli, Haemophilus influenzae, Salmonella, Shigella, Klebsiella, Serracia, Yersbnia, Proteus), rickettsia, spirochetes and some large viruses. The drug is active against strains resistant to penicillin, streptomycin, and sulfonamides. Weakly active against acid-fast bacteria, Pseudomonas aeruginosa, clostridia and protozoa.
Acts bacteriostatically. The mechanism of antibacterial action is associated with a violation of the synthesis of microbial proteins.
Drug resistance to the drug develops relatively slowly, and, as a rule, cross-resistance to other chemotherapeutic agents does not occur.
Special instructions
Due to high toxicity, it is not recommended to be used unnecessarily for the treatment and prevention of common infections, colds, flu, pharyngitis, and bacterium carriage.
Severe complications from the hematopoietic system are usually associated with the use of large doses (more than 4 g/day) for a long time. During treatment, systematic monitoring of peripheral blood patterns is necessary.
In the fetus and newborns, the liver is not developed enough to bind chloramphenicol, and the drug can accumulate in toxic concentrations and lead to the development of “gray syndrome”, so children in the first months of life are prescribed the drug only for health reasons.
Prescribe with caution to patients who have previously received treatment with cytotoxic drugs or radiation therapy.
Active ingredient
Chloramphenicol [D,L]
Composition
1 ml contains: chloramphenicol – 2.5 mg.
Excipients: boric acid.
Pregnancy
During pregnancy, it is possible if the expected effect of therapy outweighs the potential risk to the fetus (adequate and strictly controlled studies on use during pregnancy have not been conducted; the ability of chloramphenicol to penetrate the placenta should be taken into account).
FDA category of effect on the fetus is C.
When taken orally, it passes into the breast milk of nursing women and may cause serious adverse reactions in breastfed children. When applied topically, systemic absorption is possible. In this regard, nursing women should stop either breastfeeding or using the drug.
Contraindications
Hypersensitivity, diseases of the hematopoietic organs, acute intermittent porphyria, severe renal and liver dysfunction, deficiency of glucose-6-phosphate dehydrogenase, psoriasis, eczema, fungal skin diseases, neonatal period (up to 4 weeks) and early childhood.
Side Effects
Local allergic reactions.
Interaction
To prevent an increase in the inhibitory effect on hematopoiesis, combined use with sulfonamide drugs is not recommended.
Overdose
Symptoms: “gray syndrome” in premature infants and newborns when treated with high doses (the cause of development is the accumulation of chloramphenicol, due to the immaturity of liver enzymes, and its direct toxic effect on the myocardium) – bluish-gray skin color, low body temperature, irregular breathing, lack of reactions, cardiovascular failure. Mortality – up to 40%.
Treatment: hemosorption, symptomatic therapy.
Storage conditions
At a temperature not higher than 15 °C.
Keep out of the reach of children.
Store in original packaging.
Shelf life
2 years
Manufacturer
Lecco CJSC, Russia
Shelf life | 2 years |
---|---|
Conditions of storage | At a temperature not higher than 15 ° C. Keep out of reach of children. Keep in the original package. |
Manufacturer | Lekko ZAO, Russia |
Medication form | eye drops |
Brand | Lekko ZAO |
Other forms…
Related products
Buy Levomycetin, eye drops 0.25% 10 ml with delivery to USA, UK, Europe and over 120 other countries.