Levocarnil, 300 mg/ml 100 ml
€23.43 €19.52
Pharmacotherapeutic group:
Metabolic agent
ATC code: A16AA01
Pharmacological properties
Pharmacodynamics
L-carnitine is a natural substance related to B vitamins. It participates in metabolic processes as a carrier of long-chain fatty acids (palmitic acid and others) from the cytoplasm to the mitochondria where these acids undergo a process of β-oxidation to form adenosine triphosphonic acid and acetyl-CoA.
It improves protein and fat metabolism, increases the secretion and enzymatic activity of gastric and intestinal juices, improves digestion of food, reduces excess body weight and decreases muscle fat content.
It increases resistance to exercise, inhibits ketoacid formation and anaerobic glycolysis, reduces lactacidosis, promotes economical utilization of glycogen and increases its reserves in the liver and muscles. It has an anabolic and lipolytic effect. Normalizes elevated basal metabolism in hyperthyroidism: it is a periphyric (indirect) antagonist of thyroid hormones, rather than a direct inhibitor of thyroid function. It improves metabolism and energy supply of tissues.
Pharmacokinetics
It is well absorbed in the intestine, plasma concentrations reach a maximum of 3 hours and remain in therapeutic range for 9 hours. It penetrates easily into the liver and myocardium, slower in the muscles. It is excreted by the kidneys, mainly in the form of acyl esters.
Indications
The drug is used as part of the complex therapy.
- intensive physical activity and psycho-emotional stress: to increase working capacity, endurance, decrease of fatigability, including, in elderly people;
- in rehabilitation period after diseases and surgical interventions, injuries, including, to accelerate tissue regeneration;
- .
- complex therapy of chronic gastritis and chronic pancreatitis with decreased secretory function;
- complex therapy of skin diseases (psoriasis, seborrheic eczema, focal scleroderma and discoid lupus);
- neurological manifestations in vascular, toxic, and traumatic brain lesions;
- anorexia nervosa syndrome;
- in pediatric practice (treatment of children under 3 years of age under medical supervision): during nursing of premature infants, newborns after birth trauma or asphyxia; children with sluggish sucking reflex and low weight gain; with reduced muscle tone, insufficient development of motor and mental functions, as well as for the prevention of these disorders in children “at risk”; with growth retardation and weight shortage in children and teenagers under 16.
.
Composition
Active ingredient:
levocarnitine – 300 mg.
Excipients:
citric acid monohydrate – 1.2 mg,
methylparahydroxybenzoate – 0.5 mg,
propylparahydroxybenzoate – 0.2 mg,
purified water – to 1 ml.
How to take, the dosage
The drug is used in combination therapy.
Orally, 30 minutes before a meal, additionally diluted with liquid.
For convenient dosing you can use a dropper or syringe.
In case of prolonged physical and psycho-emotional exertion: from 0.75 g (2.5 ml) 3 times a day to 2.25 g (7.5 ml) 2-3 times a day.
In case of anorexia nervosa and also during rehabilitation after the diseases and surgery and injuries: 1.5 g (5 ml) 2 times a day. The course of treatment is 1-2 months.
In the treatment of chronic gastritis and chronic pancreatitis with decreased secretory function: 0.375 g (1.25 ml) 2 times a day. The course of treatment is 1-1.5 months.
For treatment of skin diseases: 0.75 g (2.5 ml). The course of treatment is 2-4 weeks.
In mild hyperthyroidism: 0.25 g (13 drops) 2 – 3 times a day. The course of treatment is 20 days. The treatment course is to be repeated after 1-2 month break or to be prescribed for 3 months without break.
In case of vascular, toxic and traumatic brain injury: 0.75 g (2.5 ml) a day. The course of treatment is 3-5 days. The course is repeated in 12-14 days if necessary.
In diseases accompanied by carnitine deficiency (primary and secondary carnitine deficiency): Up to 50-100 mg/kg (2-5 drops/kg) of body weight with multiplicity of administration 2-3 times a day. The course of treatment is 3-4 months.
Children are prescribed as an additive to sweet food (kissel, compote, juices).
Children under the age of 3 years old the dose is determined by the attending physician. From 3 to 6 years old – a single dose of 0.1 g (5 drops) 2-3 times a day, the daily dose – 0.2-0.3 g (11-16 drops). The course of treatment is 1 month. Children 6 to 12 years of age are prescribed a single dose of 0.2-0.3 g (11-16 drops) 2-3 times a day, a daily dose of 0.4-0.9 g (22-48 drops). The course of treatment is at least one month.
In case of growth retardation: 0.25 g (13 drops) 2-3 times a day. The course of treatment is 20 days. The treatment course is to be repeated after 1-2 month break or to be prescribed for 3 months without interruption.
In sports medicine and during the intensive training: 2.5 g (8.33 ml) 1-3 times a day (daily dose 2.5-7.5 g); if used for therapeutic purposes – 70-100 mg/kg/day (5-7.5 g/day). The course of treatment: 3-4 weeks in the pre-competition period. During the training process – up to 6-8 weeks.
Interaction
Glucocorticosteroids contribute to the accumulation of the drug in tissues (except the liver), other anabolics enhance the effect.
Special Instructions
Treatment of children under 3 years of age should be under the supervision of a physician.
Impact on the ability to drive vehicles, mechanisms
The drug does not affect the performance of potentially dangerous activities requiring particular attention and responsiveness (driving a car and other vehicles, working with moving mechanisms, work of dispatcher and operator, etc.)
The drug does not affect the performance of potentially dangerous activities requiring particular attention and responsiveness.
Synopsis
The popularity of Levocarnil Evalar is increasing every year, and not only among athletes. Its important role in the process of breaking down fat and energy production allows to use it as a remedy for diseases of mature age.
Levocarnil improves health in different directions:
Energy. Increases the energy resources of the body, charging it with energy, vigor and strength. It increases performance and endurance, reduces fatigue and muscle weakness, helping to become physically more active,. Improves the quality of life.
Heart function. Supports the work of the heart muscle, reduces the risk of elevated cholesterol levels because it converts excess fat into energy, preventing their deposition on the walls of blood vessels. Thus Levocarnil improves the health of people suffering from cardiovascular diseases.
Nervous system. It is used for vascular disorders of the brain and protects against many diseases of the nervous system associated with age. Levocarnil improves cognitive abilities, memory, increases mental alertness.
Immunity. It strengthens the immune system and ensures faster recovery after diseases, including respiratory infections, surgeries and injuries, as it accelerates tissue regeneration.
Contraindications
Individual intolerance.
Overdose
Symptoms: dyspeptic disorders, myasthenic disorders (in patients with uremia).
Treatment: gastric lavage, taking activated charcoal.
Pregnancy use
Due to a lack of studies, use during pregnancy and breastfeeding is not recommended.
Weight | 0.230 kg |
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Shelf life | 3 years. |
Conditions of storage | At a temperature not exceeding 25 °C. After opening, store in the refrigerator for 2 months. Keep out of reach of children. |
Manufacturer | Evalar, Russia |
Medication form | oral solution |
Brand | Evalar |
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