Lactofiltrum, tablets 500 mg 60 pcs

The pharmacological action of the drug is due to the properties of the constituent active ingredients – lignin and lactulose.

Lignin hydrolysis is a natural enterosorbent consisting of products of hydrolysis of wood components, it has high sorption activity and non-specific detoxifying effect.

Binds in the intestine and removes pathogenic bacteria and bacterial toxins, medications, salts of heavy metals, alcohol, allergens, as well as excess of certain metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea and other metabolites responsible for the development of endogenous toxicity. It is non-toxic, not absorbed, completely eliminated from the intestine within 24 hours.

Lactulose is a synthetic disaccharide whose molecule consists of galactose and fructose residues. Lactulose is not absorbed and is not hydrolyzed in the stomach and upper intestines. Lactulose released from the tablets is fermented in the large intestine as a substrate by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli.

Lactulose hydrolysis in the large intestine produces organic acids – lactic, acetic and formic acids, which inhibit the growth of pathogenic microorganisms and reduce the production of nitrogenous toxic substances.

The process described leads to increase of osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex action of the preparation is aimed at normalization of microbiocenosis of the large intestine and reduction of intensity of endogenous toxic conditions.

The use of the preparation in complex therapy of bacterial vaginosis (vaginal dysbiosis) leads to increase of efficiency of therapy including the increase of lactobacillus number in the vagina and the effective suppression of opportunistic flora growth.

Indications

Disorders of the intestinal microflora (intestinal dysbiosis), including as a result of antibiotic therapy; in complex therapy of irritable bowel syndrome, hepatitis and liver cirrhosis; allergic diseases (atopic dermatitis, urticaria), bacterial vaginosis (vaginal dysbiosis).

Pharmacological effect

The pharmacological effect of the drug is due to the properties of the active components included in the composition – lignin and lactulose.

Hydrolytic lignin is a natural enterosorbent, consisting of hydrolysis products of wood components, has high sorbing activity and a nonspecific detoxification effect.

Binds in the intestines and removes from the body pathogenic bacteria and bacterial toxins, medications, salts of heavy metals, alcohol, allergens, as well as excess of certain metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea, and other metabolites responsible for the development of endogenous toxicosis. Non-toxic, not absorbed, completely eliminated from the intestines within 24 hours.

Lactulose is a synthetic disaccharide, the molecule of which consists of galactose and fructose residues. Lactulose is not absorbed or hydrolyzed in the stomach and upper intestines. Lactulose released from the tablets in the large intestine as a substrate is fermented by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli.

As a result of the hydrolysis of lactulose in the large intestine, organic acids are formed – lactic, acetic and formic, which suppress the growth of pathogenic microorganisms and consequently reduce the production of nitrogen-containing toxic substances.

The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex effect of the drug is aimed at normalizing the microbiocenosis of the large intestine and reducing the intensity of endogenous toxic conditions.

The use of the drug in complex therapy of bacterial vaginosis (vaginal dysbiosis) leads to an increase in the effectiveness of therapy, including an increase in the number of lactobacilli in the vagina, as well as effective suppression of the growth of opportunistic flora.

Special instructions

The drug can be used in complex therapy together with other drugs, subject to the rules of separate administration.

Active ingredient

Lactulose, hydrolytic lignin

Composition

Composition per tablet:

Hydrolytic lignin (in terms of dry matter) – 355 mg

Lactulose (calculated as 100% substance) – 120 mg

Excipients:

Croscarmellose sodium – 20 mg

Magnesium stearate – 5 mg

Microcrystalline cellulose – until a tablet weighing 550 mg is obtained

Pregnancy

There are no data on the safety of using Laktofiltrum during pregnancy, lactation and in children.

Contraindications

Individual intolerance to the drug, intestinal obstruction, gastrointestinal bleeding, galactosemia. It is undesirable to use the drug during exacerbation of gastric and duodenal ulcers, intestinal atony.

Side Effects

Allergic reactions to the components of the drug are possible, rarely – flatulence, diarrhea.

Interaction

The therapeutic effect of some drugs taken orally may be reduced.

Overdose

Symptoms: constipation, abdominal pain.

Treatment: stop taking the drug.

Storage conditions

Protected from moisture and light
place at a temperature not exceeding 30°C. Keep out of the reach of children.

Shelf life

3 years

Manufacturer

ABVA RUS, Russia