Kostarox, 120 mg 7 pcs.

NSAID. Selective COX-2 inhibitor, in therapeutic concentrations blocks formation of prostaglandins and has anti-inflammatory, analgesic and antipyretic effect.

Indications

Symptomatic therapy for osteoarthritis, rheumatoid arthritis, ankylosing spondylitis; pain and inflammatory symptoms associated with acute gouty arthritis; short-term treatment of pain associated with dental surgery.

Active ingredient

Etoricoxib

Composition

1 tablet etoricoxib 120 mg

Interaction

In patients receiving warfarin, etoricoxib at a dose of 120 mg/day was accompanied by an increase of approximately 13% in MHO and prothrombin time.

Directions for use

The drug is taken orally in a dose of 60-120 mg once a day.

Special Instructions

Use with caution when there is a history of gastrointestinal ulcers, Helicobacter pylori infection, in elderly patients, patients who have received long-term NSAIDs, severe somatic diseases, dyslipidemia/hyperlipidemia, diabetes, arterial hypertension, edema and fluid retention, smoking, patients with IQ less than 60 ml/min, concomitant therapy with the following medicinal agents anticoagulants (e.g., warfarin), antiaggregants (e.g., acetylsalicylic acid, clopidogrel), GCS (e.g., prednisolone), selective serotonin reuptake inhibitors (e.g., citalopram, fluoxetine, paroxetine, sertraline), in chronic alcoholism.

Contraindications

Complete or incomplete combination of bronchial asthma, recurrent nasal or paranasal sinus polyposis and intolerance to acetylsalicylic acid and other NSAIDs (including history).

Side effects

Digestive system disorders: frequent – epigastric pain, nausea, diarrhea, dyspepsia, flatulence; sometimes – bloating, belching, increased peristalsis, constipation, dry oral mucosa, gastritis, gastric or duodenal ulcer, irritable bowel syndrome, esophagitis, oral mucosa ulcers, vomiting; very rarely – GI ulcers (with bleeding or perforation), hepatitis.

Pregnancy use

The drug is contraindicated during pregnancy and lactation.

Similarities

Arcoxia, Atorica tablets, Bixitor, Etoricoxib-Teva