Knightwell capsules 645 mg, 20 pcs.

Nightwell is a combination of 4 natural herbal ingredients, enhanced with magnesium and vitamin B₆ to help relieve emotional tension, sleep disorders and insomnia.

The ingredients in the Knightwell Complex help normalize and improve the quality of sleep and ensure a relaxing night’s sleep and the natural process of falling asleep.

The positive effects of Nightwell on the human nervous system are due to the complex influence of the herbal ingredients, magnesium and vitamin B₆, which it contains, on the production of serotonin and the increased activity of GABA (gamma-aminobutyric acid), which participates in initiating and maintaining sleep: GABA helps reduce arousal and inhibits neurotransmitters that maintain the waking state. In addition, GABA is important for mitigating stress responses.

Hops has a calming effect on the CNS. The main mechanism of action of the components making up common hops is linked to an increase in the activity of GABA, the main neurotransmitter involved in central inhibition, including sleep patterns. GABA reduces agitation and has a calming effect. Hops also have an effect on the production of serotonin and adenosine, which are actively involved in the mechanisms of organization of night sleep. Thus, hops have a mild sedative effect, modulate the rhythm of sleep/wakefulness and promote the initiation of sleep, reduce increased nervous excitability, affecting the quality of sleep and the time of going to sleep. Under the influence of GABA, brain energy processes are activated, tissue respiratory activity is increased, brain utilization of glucose is improved, blood supply is improved, which in turn improves cognitive functions: concentration, improved perception of information and memorization, memory, performance. Helps to normalize cyclic processes in women and eliminate vegetative manifestations.

Passiflora incarnata/strastoflower is one of the main sedative herbal remedies. It helps to reduce anxiety and influences the activation of mechanisms of initiation of natural physiological sleep. Relieves manifestations of mental tension, as well as accompanying disorders of the autonomic nervous system, including palpitations, increased sweating, reddening of the face.

Passiflora improves mood by inhibiting the monoamine oxidase (MAO) enzyme in the brain tissue, which results in increased production of serotonin, one of the main neurotransmitters often called the “good mood hormone” and the “happiness hormone”. In turn, serotonin is a precursor of melatonin, which plays a key role in the process of sleep organization, influencing the quality and depth of sleep, and is also involved in the regulation of circadian and seasonal cycles, including the alternation of sleep and wakefulness. Thus, passiflora through the activation of melatonin synthesis contributes to the natural process of falling asleep, improves sleep and does not cause unpleasant heavy feelings upon awakening.

Melissa medicinalis has a mild sedative effect (reduces irritability), which leads to a decrease in nervous agitation and improves the process of falling asleep.

Valeriana medicinalis has a calming effect on the CNS and regulates cardiac activity. Valerian root has been found to reduce the subjective experience of stress without reducing memory and attention functions.

Magnesium plays a central role in the regulation of nervous activity and neuromuscular transmission. It is a cofactor for the synthesis of ATP and also participates in the regulation of cellular energy expenditure through the diurnal cycle. The most important role of magnesium is that it serves as a natural anti-stress factor, inhibits the development of excitation processes in the CNS, reduces the body’s sensitivity to external influences. Magnesium deficiency can lead to such manifestations as increased irritability, fatigue, sleep disorders. Replenishment of magnesium deficiency helps to increase resistance to stress, relax muscles, reduce fatigue and agitation of the nervous system, normalize sleep and increase efficiency.

Vitamin B₆ (pyridoxine) has a significant and selective modulating effect on central serotonin and GABA synthesis. Vitamin B₆ is directly involved in protein metabolism, amino acid synthesis and transport, lipid metabolism, energy production in the body, peripheral nervous system neurotransmitter synthesis, and supports transport protein synthesis in axial nerve cell cylinders. Vitamin B₆ helps improve metabolism in brain tissue by participating in amino acid metabolism. Helps to improve brain function, improves memory and mood.

Nightwell, thanks to the ingredients it contains, promotes:

– relaxation and reduction of nervous excitability, which helps to fall asleep faster (easier);

– To activate the mechanism of normal physiological sleep and improve the quality and depth of sleep;

– reduces fatigue;

– improves concentration, memory and performance.

Indications

As a dietary food supplement – an additional source of vitamin B ₆ and magnesium.

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Composition

Microcrystalline cellulose (carrier),

Magnesium oxide, gelatin,

Passiflora incarnata herb extract,

Honeycomb extract.p> extract of copulas of common hops,

extract of lemon balm leaves,

extract of Valeriana officinalis roots,

silica dioxide (anti-caking agent),

vitamin B₆ (pyridoxine hydrochloride),

Magnesium salts of fatty acids (anti-caking agent),

Titanium dioxide (dye),

Indigo carmine (dye).

Directions for use

Adults are prescribed 1 caps./day with an evening meal or before going to bed.

The duration of treatment is 2-3 weeks. If necessary, the course of treatment may be repeated in a month.

Special Instructions

Biologically active food supplement, is not a medicine.

Consult a physician before use.

Contraindications

• pregnancy,
• lactation period (breastfeeding),
• individual intolerance to the components.

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