Klenzit, gel 0,1% 30 g
€27.03 €22.53
The active ingredient of the drug is a retinoid derivative – Adapalene, which has anti-inflammatory and comedolytic activity. Adapalene participates in normalization of epidermal differentiation and keratinization processes, inhibits formation of microcomedones and reduces manifestations of inflammation.
The mechanism of action of the active ingredient of Klenzit lies in its ability to influence specific gamma-receptors of the epidermal cells of the skin, reducing their adhesive surface in the mouths of oil-hair follicles.
In vivo and in vitro studies have proven that Adapalen has a strong anti-inflammatory action due to its effect on inflammatory factors.
Inhibits the metabolism of arachidonic acid and migration of leukocytes.
When the gel is applied externally, the systemic absorption of its active ingredient Adapalen is quite low, about 4% of the used dose. From the systemic bloodstream, excreted by the liver.
Indications
Common (adolescent) acne (acne vulgaris).
Pharmacological effect
The active substance of the drug is a retinoid derivative – Adapalene, which exhibits anti-inflammatory and comedolytic activity. Adapalene takes part in the normalization of the processes of epidermal differentiation and keratinization, inhibits the formation of microcomedones and reduces the manifestations of the inflammatory process.
The mechanism of action of the active substance of the drug Klenzit lies in its ability to influence specific gamma receptors of epidermal cells of the skin, reducing their adhesive surface at the mouths of the pilosebaceous follicles.
In vivo and in vitro studies have proven that Adapalene has a pronounced anti-inflammatory effect due to its influence on the factors of the inflammatory process.
Inhibits the metabolism of arachidonic acid and the migration of leukocytes.
When the gel is applied externally, the systemic absorption of its active substance Adapalene is quite low, about 4% of the dose used. From the systemic circulation, excreted by the liver.
Special instructions
If the drug accidentally gets on the mucous membranes of the eyes, mouth or nose, rinse them thoroughly with warm water.
Direct sunlight should be avoided as skin irritation may occur. Treatment can be continued if sun exposure is kept to a minimum by wearing sunglasses and hats.
The simultaneous use of cosmetics with a drying and irritating effect on the skin (for example, perfumes or ethanol-containing products) is not recommended.
Adapalene applied to the skin in the evening can be combined with acne medications used in the morning.
Active ingredient
Adapalene
Composition
Active ingredient:
adapalene 1 mg.
Excipients:
disodium edetate,
carbomer 940 (carbopol 940),
propylene glycol,
methyl parahydroxybenzoate,
phenoxyethanol,
poloxamer 407,
sodium hydrochloride,
purified water.
Pregnancy
It is not recommended to use the drug during pregnancy and lactation (breastfeeding).
Contraindications
Hypersensitivity to the components of the drug;
Pregnancy;
Lactation period (breastfeeding).
The drug should be used with caution for dermatitis and eczema.
Side Effects
Dermatological reactions: skin irritation (treatment should be suspended until skin irritation disappears or reduce the frequency of use of Klenzit).
Storage conditions
In a place protected from light, at temperatures below 25 °C
Shelf life
3 years
Manufacturer
Glenmark Pharmaceuticals Ltd, India
Shelf life | 3 years |
---|---|
Conditions of storage | In a light-protected place, at a temperature below 25 °C |
Manufacturer | Glenmark Pharmaceuticals Ltd, India |
Medication form | gel for external use |
Brand | Glenmark Pharmaceuticals Ltd |
Other forms…
Related products
Buy Klenzit, gel 0,1% 30 g with delivery to USA, UK, Europe and over 120 other countries.