KIP, lyophilizate 300 mg 1 dose 5 pcs

Pharmacodynamics

Pharmacotherapeutic group. Immunoglobulin.

ATC code. J06BA.

Pharmacological properties. Pharmacological properties of the drug are caused by the content of its constituent immunoglobulins of classes IgG, IgA, IgM. The drug increases specific immunity due to immunoglobulins that have local effect in the lumen of small and large intestine, blocking microbial cell receptors, thereby reducing the adsorption of microbes on the cells of the epithelium of the intestinal mucosa and inhibiting the reproduction of adsorbed microbial cells, weakening or preventing the development of the infection.

Indications

The drug is used as part of complex therapy for viral and bacterial intestinal infections in children from 1 month of age and adults.

Pharmacological effect

Pharmacodynamics

Pharmacotherapeutic group. Immunoglobulin.

ATX code. J06BA.

Pharmacological properties. The pharmacological properties of the drug are determined by the content of its constituent immunoglobulins of the classes IgG, IgA, IgM. The drug increases specific immunity due to the content of immunoglobulins, which have a local effect in the lumen of the small and large intestine, blocking microbial cell receptors, thereby reducing the adsorption of microbes on the epithelial cells of the intestinal mucosa and inhibiting the proliferation of adsorbed microbial cells, weakening or preventing the development of the infectious process.

Special instructions

The drug is not suitable for use in bottles with damaged integrity, labeling, the presence of coarse foreign inclusions, changes in physical properties, expired expiration dates, or improper storage.

Precautions for use

The safety of the use of human normal immunoglobulin preparations during pregnancy and during breastfeeding has not been studied in controlled clinical studies, therefore their administration to pregnant women and women during breastfeeding should be done with caution. Long-term experience in the clinical use of normal human immunoglobulin preparations suggests that one should not expect a negative effect of such drugs on the course of pregnancy, on the fetus or on the child during breastfeeding.

Active ingredient

Human immunoglobulin normal IgG, IgA, IgM

Composition

Active ingredient:

– human blood plasma proteins, of which immunoglobulins of the IgG, IgA, IgM classes are at least 97% – 300 mg.

Excipients:

– glycine (aminoacetic acid) – 150 mg.

The drug does not contain preservatives or antibiotics.

Pregnancy

The safety of using human normal immunoglobulin preparations during pregnancy and breastfeeding has not been studied in controlled clinical studies, therefore their use in pregnant women and women during breastfeeding should be done with caution. Experience in the clinical use of immunoglobulin allows us to conclude that there is no negative effect on the course of pregnancy, on the fetus or on the child during breastfeeding.

Contraindications

– a history of allergic reactions to human blood products;

– hypersensitivity to the components included in the drug.

Side Effects

Local allergic reactions in the form of local polymorphic rashes on the skin are possible. If a skin rash appears, the drug is continued with antihistamines.

Interaction

No undesirable interactions with other drugs were noted. Can be used in combination with antibiotics, chemotherapeutic agents and bacteriophages.

Overdose

No cases of drug overdose have been reported.

Short product description

KIP is a lyophilized protein solution containing immunoglobulins of the classes IgG, IgA, IgM, isolated from the blood plasma of healthy donors.

Storage conditions

In a dry place, protected from light, at a temperature of 2–10 °C.

Shelf life

3 years.

Manufacturer

Microgen NPO, Russia