Ketonal, gel 2.5% 100 g

Symptomatic therapy of painful and inflammatory processes of different genesis, including:

– rheumatoid arthritis and periarthritis;

– ankylosing spondylitis (Bechterew’s disease);

– psoriatic arthritis;

– reactive arthritis (Reiter’s syndrome);

– osteoarthritis of various localizations;

– tendinitis, bursitis;

– myalgia; <

– neuralgia;

– sciatica;

– musculoskeletal injuries (including sports.

– injuries of the musculoskeletal system (including sports), muscle and ligament contusions, sprains, tears of ligaments and tendons of muscles.

Active ingredient

Composition

Active substances:

ketoprofen 25 mg

Excipients:

(carbomer – 20 mg, trolamine (triethanolamine) – 37 mg,

p> ethanol 96% – 285 mg,

lavender oil (lavender essential oil) – 0.28 mg,

water – 632.72 mg) – 1 g.

How to take, the dosage

For external use.

A small amount of gel (about 3-5 cm) is applied with gentle rubbing movements in a thin layer to the skin over the lesion 1-2 times a day.

Please note that 5 cm of the gel gives 100 mg of ketoprofen; 10 cm gives 200 mg of ketoprofen. The maximum daily dose when using the gel is 200 mg.

The occlusive dressing is not recommended.

Ketonal® Gel can be used in combination with other forms of Ketonal (capsules, tablets, rectal suppositories).

The duration of treatment without medical advice should not exceed 14 days.

Interaction

Since the concentration of the drug in the blood plasma is extremely low, manifestations of interaction symptoms with other drugs (similar symptoms with systemic use) are possible only with frequent and prolonged use.

The simultaneous use of other forms for topical and external use (ointments, gels) containing ketoprofen or other NSAIDs is not recommended.

Concomitant use of acetylsalicylic acid reduces the degree of binding of ketoprofen to blood plasma proteins.

Ketoprofen reduces excretion of methotrexate and contributes to its toxicity.

Interaction with other medicinal products and effect on their excretion are not significant.

Patients taking coumarin-containing anticoagulants are recommended to be treated under medical supervision.

Special Instructions

Avoid getting the gel in the eyes, on the skin around the eyes, mucous membranes.

If any side effects occur, discontinue use of the product and consult a physician.

If a patient forgets to apply the gel, it should be used at the time the next dose is due, but do not double it.

Ketonal® Gel for external use may be used in combination with other dosage forms of Ketonal® (capsules, tablets, suppositories). The total daily dose regardless of the dosage form should not exceed 200 mg.

In case of skin reactions, including those developed when combined with octocrylene-containing drugs, treatment should be stopped immediately.

In order to reduce the risk of photosensitivity, it is recommended that the areas of skin treated with the gel be protected with clothing throughout the entire period of treatment and for a further 2 weeks following discontinuation of the gel.

Do not use as an occlusive dressing.

Wash hands thoroughly after each application.

Influence on driving and operating ability

There are no reports of adverse effects of the product Ketonal® Gel on the ability to drive vehicles and other potentially dangerous activities requiring concentration and quick psychomotor reaction.

Contraindications

– hypersensitivity to the components of the drug;

– hypersensitivity to salicylates, thiaprofenoic acid or other NSAIDs, phenofibrate, UV blockers, fragrances;

– Skin integrity problems (eczema, sore throat, open or infected wound);

– A history of bronchial asthma attacks triggered by taking NSAIDs and salicylates.

He has a history of photosensitivity.including indirect sunlight and UV exposure in a tanning bed for the whole period of treatment and 2 weeks after discontinuation of the treatment;

– 3rd trimester of pregnancy;

– childhood age less than 15 years.

With caution: impaired hepatic and/or renal function, gastrointestinal erosive lesions, blood diseases, bronchial asthma, chronic heart failure.

Side effects

Most common local reactions.

Frequency of adverse reactions: very common (≥1/10), common (≥1/100 and

Allergic reactions: very rare – angioedema, anaphylaxis.

Skin and skin appendages: infrequent – erythema, itching, burning, eczema, transient dermatitis of mild severity; rarely – urticaria, rash, photosensitization, bullous dermatitis, purpura, erythema multiforme, lichenoid dermatitis, skin necrosis, Stevens-Johnson syndrome; very rarely – a single case of severe contact dermatitis (against the background of poor hygiene and insolation), a single case of severe generalized photodermatitis, toxic epidermal necrolysis.

Respiratory system disorders: very rare – asthmatic attacks (as a variant of allergic reaction).

Urinary system disorders: very rare – a single case of deterioration of renal function in a patient with chronic renal failure; in single cases – interstitial nephritis.

Overdose

Symptoms: irritation, erythema, itching.

Treatment: Stop using the drug, rinse skin thoroughly with running water. The patient should see a doctor.

Pregnancy use

The drug is contraindicated for use in the third trimester of pregnancy.

The use in I and II trimesters is possible in cases when the expected benefits to the mother exceed the potential risk to the fetus.

The use of the drug Ketonal® during lactation (breast-feeding) is not recommended.

Similarities