Ketodexal, 25 mg/ml 2 ml 5 pcs

Osteochondrosis, Renal colic, Toothache, Pain after injuries and operations, Common acne (vulgar), Joint pain (arthralgia), Arthrosis and arthritis, Rheumatoid arthritis, Lumbago, Sciatica, Radiculitis

Pain syndrome treatment of different genesis (including post-operative pain, pain caused by bone metastases, post-traumatic pain, pain caused by cramps of the kidneys, algodysmenorrhea, sciatica, radiculitis, neuralgia, toothache);

Symptomatic treatment of acute and chronic inflammatory, inflammatory-degenerative and metabolic diseases of the musculoskeletal system

Active ingredient

Composition

1 ml of the drug contains:

The active ingredient:

dexketolrofen trometamol in terms of dexketolrofen – 25.0 mg;

Ancillary components:

Ethanol 96%,

Sodium chloride,

1 M sodium hydroxide solution,

water for injection.

How to take, the dosage

It is taken orally. The average recommended single dose is 12.5 mg – 1-6 times/day every 4-6 hours as needed or 25 mg 1-3 times/day every 8 hours.

The maximum daily dose is 75 mg. The duration of use is not more than 3-5 days.

For patients with hepatic or renal dysfunction and the elderly, the starting dose is not more than 50 mg/day.

Interaction

Concomitant use of dexectoprofen with other NSAIDs may increase the risk of side effects.

Concomitant use with lithium preparations may increase the concentration of the latter in blood plasma.

With caution, use Dexectoprofen less than 24 hours before starting or after therapy with methotrexate, because the plasma concentrations of the latter (and therefore toxicity) may increase.

There have been some cases of bleeding when concomitant use of NSAIDs and anticoagulants.

Special Instructions

Caution should be exercised when prescribing the drug in elderly patients, patients with allergic reactions, patients with systemic connective tissue diseases and patients with hematopoiesis disorders.

Patients should be informed that if any side effects occur and there is no clinical effect within 3-5 days of treatment, the physician should be told.

Particular caution is required when using dexketoprofen concomitantly with phenytoin, sulfonamides and drugs that reduce blood clotting.

Impact on driving and operating machinery

As dexketoprofen may cause impaired ability to concentrate, caution should be used in patients engaged in potentially hazardous activities requiring increased attention and rapid psychomotor reactions.

Contraindications

Gastric and duodenal ulcer, gastrointestinal bleeding, active bleeding of different genesis, increased bleeding, anticoagulant therapy, Crohn’s disease, nonspecific ulcerative colitis, bronchial asthma (including in anamnesis).

, severe heart failure, renal failure, liver failure, pregnancy, lactation, hypersensitivity to dexectoprofen or other NSAIDs.

Side effects

Digestive system disorders: heartburn, abdominal pain; rarely – gastrointestinal erosive ulcers.

Nervous system disorders: headaches, dizziness, nervousness, sleep disturbances, paresthesias.

Cardiovascular system: palpitations, increased BP.

Allergic reactions: skin rash, bronchospasm.

Others: chills, edema of the extremities, photosensitization; rarely – changes in peripheral blood count, renal dysfunction.

Similarities