Iodoxide, vaginal suppositories 200 mg 10 pcs
€10.71 €9.37
Antiseptic drug. It blocks amino groups of cellular proteins. It has a wide range of antimicrobial action. It is active against bacteria (including E. coli, Staphylococcus aureus), fungi, viruses, protozoa.
The active ingredient of the drug – iodine – is in the form of complex with polyvinylpyrrolidone (povidon), related to iodophores that bind iodine. Concentration of active iodine is 0.1-1%.
In contact with skin and mucous membranes iodine is gradually and evenly released with bactericidal effect on microorganisms.
A thin colored layer remains on the application site until all iodine is released.
Absorption and distribution
In contact with the mucous membranes povidone-iodine may be absorbed and its content in the blood (concentration returns to the initial value in 7-14 days after the last use of the drug).
In patients with normal thyroid function increased absorption of iodine does not cause significant changes in its hormonal function.
Excretion
Iodine is excreted mainly by the kidneys. The half-life (T1/2) after intravaginal administration is about 48 hours.
Indications
Colorectal (candida), inflammation of the female genitalia, Trichomoniasis, Vaginitis
- acute and chronic inflammatory vaginal diseases (trichomonas, fungal, viral, nonspecific, mixed infections);
- bacterial vaginitis;
- prevention of infectious and inflammatory complications before gynecological interventions (artificial termination of pregnancy, installation and removal of the IUD, cervical diathermic coagulation, hysterosalpingography and others).
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Active ingredient
Povidone-Yodine
Composition
Active ingredient:
Povidone iodine (povidone iodine 30/06) – 200.0 mg (at 11% povidone iodine activity; in case of other drug activity, decrease or increase the amount of base accordingly);
Associates:
Polyethylene oxide base:
Macrogol-1500 (polyethylene oxide-1500) – 2.66 g,
Macrogol-400 (polyethylene oxide-400) – 0.14 g.
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How to take, the dosage
Intravaginally. Inserted deep into the vagina while lying on the back.
In acute vaginitis – 1 suppository 2 times a day for 7 days; in subacute and chronic vaginitis – 1 suppository 1 time a day before bedtime for 14 days (regardless of the phase of the menstrual cycle).
The course of treatment may be prolonged if necessary.
Interaction
Povidone iodine is incompatible with oxidizing agents, alkali salts and substances with acid reaction.
It is not recommended to use povidone iodine simultaneously with hydrogen peroxide and agents containing mercury, silver and enzymes.
Special Instructions
In the presence of blood the bactericidal effect of povidone iodine may decrease.
In case of nonmaniphestral hyperthyroidism and other thyroid diseases (especially in elderly patients) the drug is used only under strict indications and under constant medical supervision.
Due to oxidative properties of povidone iodine its traces may lead to false positive results of some types of tests to detect occult blood in stools, as well as blood or glucose in urine.
During the use of povidone iodine may decrease iodine absorption by the thyroid gland, which may affect the results of some diagnostic studies (such as thyroid scintigraphy,
determination of protein-bound iodine, measurements using radioactive iodine), and also possible interaction with iodine preparations used to treat thyroid diseases.
To obtain undistorted results of thyroid scintigraphy after prolonged therapy with povidone-iodine it is recommended to withstand a sufficiently long period of time without this drug.
If symptoms of hyperthyroidism occur during the course of treatment, thyroid function should be checked.
Caution should be exercised with regular use of the drug in patients with previously diagnosed renal insufficiency.
Regular use of the drug Iodoxide® in patients receiving lithium preparations should be avoided.
Caution is recommended when introducing the vaginal suppositories to virgins.
The color on the skin and tissues is easily washed away with water.
The suppositories have spermicidal effect therefore it is not recommended to be used by those who intend to become pregnant.
During the period of suppositories use the sanitary pads may be recommended.
After contact with the drug avoid getting it in the eyes.
Effect on the ability to drive vehicles and work with mechanisms
Does not affect the ability to drive vehicles and other mechanisms.
Contraindications
- hypersensitivity to the components of the drug;
- thyrotoxicosis;
- During dermatitis herpetiformis;
- Hypersensitivity to the ingredientsThyroid adenoma;
- simultaneous therapy with radioactive iodine;
- the period of neonatality (especially in premature infants).
With caution:
- chronic renal failure;
- pregnancy (II and III trimester);
- breastfeeding.
Side effects
Hypersensitivity reactions to the drug at the site of application: hyperemia, itching.
Allergic reactions are possible, including contact dermatitis with the formation of psoriasis-like red small bullous elements.
In case of such phenomena the drug should be discontinued.
Similarities
Betadine, Povidon-Yod, Braunodine B.Brown
Weight | 0.040 kg |
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Shelf life | 3 years. Do not use the drug after the expiration date stated on the package. |
Conditions of storage | In the dark place at a temperature not exceeding 25 ° C. Keep out of reach of children. |
Manufacturer | Nizhpharm AO, Russia |
Medication form | vaginal suppositories |
Brand | Nizhpharm AO |
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