Iodoxide, vaginal suppositories 200 mg 10 pcs

Antiseptic drug. It blocks amino groups of cellular proteins. It has a wide range of antimicrobial action. It is active against bacteria (including E. coli, Staphylococcus aureus), fungi, viruses, protozoa.

The active ingredient of the drug – iodine – is in the form of complex with polyvinylpyrrolidone (povidon), related to iodophores that bind iodine. Concentration of active iodine is 0.1-1%.

In contact with skin and mucous membranes iodine is gradually and evenly released with bactericidal effect on microorganisms.

A thin colored layer remains on the application site until all iodine is released.

Absorption and distribution

In contact with the mucous membranes povidone-iodine may be absorbed and its content in the blood (concentration returns to the initial value in 7-14 days after the last use of the drug).

In patients with normal thyroid function increased absorption of iodine does not cause significant changes in its hormonal function.

Excretion

Iodine is excreted mainly by the kidneys. The half-life (T1/2) after intravaginal administration is about 48 hours.

Indications

Active ingredient

Composition

Active ingredient:

Povidone iodine (povidone iodine 30/06) – 200.0 mg (at 11% povidone iodine activity; in case of other drug activity, decrease or increase the amount of base accordingly);

Associates:

Polyethylene oxide base:

Macrogol-1500 (polyethylene oxide-1500) – 2.66 g,

Macrogol-400 (polyethylene oxide-400) – 0.14 g.

How to take, the dosage

Intravaginally. Inserted deep into the vagina while lying on the back.

In acute vaginitis – 1 suppository 2 times a day for 7 days; in subacute and chronic vaginitis – 1 suppository 1 time a day before bedtime for 14 days (regardless of the phase of the menstrual cycle).

The course of treatment may be prolonged if necessary.

Interaction

Special Instructions

Contraindications

With caution:

Side effects

Similarities