Pharmacodynamics.
Jodantipyrine has anti-inflammatory, immunostimulatory and interferonogenic properties. It stabilizes biological membranes and inhibits virus penetration into the cell. It is an active inducer of alpha and beta interferon, stimulates cellular and humoral immunity. It is active against tick-borne encephalitis virus, hemorrhagic fever with renal syndrome.
Pharmacokinetics.
Fastly absorbed from the gastrointestinal tract, bioavailability is 80%. Up to 95% is metabolized in the liver. Urinary excretion through the kidneys by active transport to the renal tubules: 3-5% unchanged, 80-90%) – inactive metabolites. It has high affinity to tissue proteins. Binding to blood proteins is 25%. The elimination half-life is about 6 hours.
Indications
Active ingredient
Composition
Active ingredients:Iodantipyrine – 0,1 g
Additional ingredients:potato starch, glucose, magnesium stearate, polyvinylpyrrolidone low molecular weight medical.
How to take, the dosage
Iodantinopyrin tablets are taken orally after meals.
Prevention and treatment of tick-borne encephalitis. Treatment:
About 300 mg (3 tablets) – 3 times a day for the first 2 days; 200 mg (2 tablets) – 3 times a day for the next 2 days; 100 mg (1 tablet) – 3 times a day for the next 5 days.
Prevention:
Treatment of hemorrhagic fever with renal syndrome (HFRS).
The drug should be given within five days of onset.
200 mg (2 tablets) 3 times daily for the first four days;
100 mg (1 tablet) 3 times daily for the next five days.
Interaction
Special Instructions
Synopsis
Contraindications
Side effects
Weight | 0.017 kg |
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Shelf life | 3 years. Do not use after the expiration date stated on the package. |
Conditions of storage | Store in a dry, light-protected place at a temperature not exceeding 25 °С. Keep out of reach of children. |
Manufacturer | Pharmstandard-Leksredstva, Russia |
Medication form | pills |
Brand | Pharmstandard-Leksredstva |
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