Ibuprofen-Acrihin, 100 mg/5 ml orange 100 ml suspension

Non-steroidal anti-inflammatory drug, a derivative of phenylpropionic acid.

It has anti-inflammatory, analgesic and antipyretic effects. The drug effect is due to inhibition of prostaglandin synthesis by blocking the enzyme cyclooxygenase.

Inhibits platelet aggregation. With prolonged use it has a desensitizing effect.

Indications

Active ingredient

Composition

How to take, the dosage

In rheumatoid arthritis 800 mg 3 times a day is prescribed.

In osteoarthritis and ankylosing spondylitis Ibuprofen is used in 400-600 mg 3-4 times a day.

In juvenile rheumatoid arthritis the drug is used in a dose of 30-40 mg/kg body weight per day.

In case of trauma of soft tissues, sprain of ligaments the drug is prescribed in dose of 600 mg 2-3 times a day.

In moderate-intensity pain syndrome the drug is prescribed in 400 mg 3 times a day. Maximal daily dose is 2.4 g.

Interaction

In concomitant administration Ibuprofen may decrease the diuretic effect of furosemide.

When co-administration Ibuprofen increases the effect of diphenin, coumarin anticoagulants, oral hypoglycemic agents.

Special Instructions

The drug is prescribed with caution in patients with impaired liver function, renal function, cardiovascular system diseases, with a history of peptic ulcer and/or duodenal ulcer, gastrointestinal bleeding.

Compared with other NSAIDs, Ibuprofen has the least ulcerogenic effect on the gastrointestinal mucosa.

When using the drug for a long time it is necessary to monitor the liver and/or kidney function and peripheral blood picture.
During pregnancy the drug should be used only if prescribed by the doctor.

Contraindications

Side effects

Possible: nausea, anorexia, flatulence, constipation, heartburn, diarrhea, dizziness, headache, agitation, insomnia, allergic reactions in the form of skin rash, visual disturbances.

There have been cases of gastrointestinal erosive and ulcerative lesions.

Rarely: bleeding from the gastrointestinal tract, aseptic meningitis, bronchospasm.

Similarities