Hexoral, 0.1% solution 200 ml
€14.54 €12.60
Hexoral is deodorizing, antiseptic, enveloping, hemostatic, antifungal, analgesic.
Pharmacodynamics
The antimicrobial action of the drug Hexoral is associated with the inhibition of oxidative reactions of bacterial metabolism (thiamine antagonist). The product has a wide spectrum of antibacterial and antifungal activity, particularly against Gram-positive bacteria and fungi of the genus Candida, but Geksoral may also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg/ml, the drug suppresses most strains of bacteria.
The development of resistance has not been observed. Hexatidine has a weak anesthetic effect on the mucous membranes.
Pharmacokinetics
Hexethidine adheres very well to the mucosa and is almost never absorbed.
After a single application of the active ingredient, traces of it are detectable on the gum mucosa within 65 hours. In the plaques on the teeth the active concentrations remain for 10-14 hours after application.
Indications
inflammatory and infectious diseases of the oral cavity and pharynx;
severe, accompanied by fever or purulent diseases of the oral cavity and pharynx, requiring the prescription of antibiotics and sulfonamides, tonsillitis (as part of complex therapy);
tonsillitis (including tonsillitis with damage to the lateral ridges, Plaut-Vincent’s tonsillitis);
pharyngitis;
gingivitis and bleeding gums;
periodontopathies (periodontal diseases and their symptoms);
stomatitis (inflammation of the oral mucosa), glossitis (inflammation of the tongue), aphthous ulcers (painful inflammation with superficial tissue defects) – to prevent superinfections;
infection of the alveoli (sockets of teeth) after tooth extraction;
fungal infections of the oral cavity and pharynx, especially candidal stomatitis (thrush);
before and after operations in the oral cavity and pharynx;
additional oral hygiene for general diseases;
elimination of bad breath, especially in the case of decaying tumors of the oral cavity and pharynx;
an aid in the treatment of colds.
Pharmacological effect
Hexoral – deodorizing, antiseptic, enveloping, hemostatic, antifungal, analgesic.
Pharmacodynamics
The antimicrobial effect of the drug Hexoral is associated with the suppression of oxidative reactions of bacterial metabolism (thiamine antagonist). The drug has a wide spectrum of antibacterial and antifungal effects, in particular against gram-positive bacteria and fungi of the genus Candida, however, Hexoral can also have an effect in the treatment of infections caused, for example, by Pseudomonas aeruginosa or Proteus. At a concentration of 100 mg/ml, the drug inhibits most strains of bacteria.
No development of resistance was observed. Hexethidine has a weak anesthetic effect on the mucous membrane.
Pharmacokinetics
Hexethidine adheres very well to the mucous membrane and is practically not absorbed.
After a single use of the active substance, traces of it are found on the gum mucosa within 65 hours. In plaques on teeth, active concentrations remain for 10–14 hours after application.
Special instructions
There are no special instructions.
Hexoral® solution for topical use can be used to rinse the mouth and throat only if the patient can spit out the solution after rinsing.
Hexoral® solution for topical use contains ethanol 96% (4.33 g/100 ml solution).
Use in pediatrics
In children, the drug can be used from an age when there is no danger of uncontrolled swallowing when using the solution.
Active ingredient
Hexethidine
Composition
Active ingredient:
hexethidine 0.1 g/100 ml (0.1%);
Excipients:
ethanol 96% (4.33 g/100 ml solution);
polysorbate 60;
peppermint oil;
anise oil;
citric acid monohydrate;
sodium saccharin;
levomenthol;
methyl salicylate;
clove oil;
eucalyptus oil;
azorubine 85% (E122);
purified water
Pregnancy
Pregnant and lactating women should consult a doctor before using the drug.
Contraindications
Hypersensitivity to any of the components of the drug; children’s age (up to 3 years).
Side Effects
In some cases, hypersensitivity reactions to the drug developed.
With prolonged use, taste disturbance may occur.
Interaction
Drug interactions with Hexoral® have not been described.
Overdose
Hexethidine in the indicated dosage is non-toxic.
Symptoms: Ingestion of large quantities of the drug leads to vomiting, so significant absorption is not expected. No cases of alcohol poisoning due to overdose have been described.
Acute alcohol poisoning is very unlikely, but theoretically possible if a large dose of the drug is swallowed by a small child.
Treatment: gastric lavage is necessary within 2 hours after ingestion of an excess dose.
Carrying out symptomatic therapy, as for alcohol intoxication. In any case of overdose, the patient should immediately consult a doctor.
Storage conditions
In a place protected from light, at a temperature not exceeding 25 °C.
Shelf life
2 years
Manufacturer
Delpharm Orleans, France
Shelf life | 2 years |
---|---|
Conditions of storage | In a light-protected place at a temperature not exceeding 25 °C. |
Manufacturer | Delpharm Orleans, France |
Medication form | topical solution |
Brand | Delpharm Orleans |
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