Gynoflor E, vaginal tablets 6 pcs

Gynoflor E is an antimicrobial and antiseptic agent used in gynecology. It contains active substances identical to those naturally found in the human vagina. A healthy vagina is in a state of biological balance and has a natural defense mechanism against infections.

Lactobacilli bacteria are a major part of this defense mechanism; they produce lactic acid and other substances that have anti-infective effects. The production of lactic acid results in an acidic environment that promotes Lactobacilli bacteria and inhibits the development of pathogens.

Disruption or destruction of the vaginal lactic acid flora can occur due to treatment with certain drugs (e.g. antibiotics), due to local infections, serious systemic diseases or improper hygiene measures (vaginal rinses and showers). Gynoflor E contains high doses of viable Lactobacilli bacteria to help restore the natural vaginal flora. In addition to the natural flora, the condition of the vaginal epithelium is very important for the natural defense mechanism of the vagina. It can be damaged by fluctuating or deficient hormone levels (especially during or after menopause) and vaginal infections.

The second active ingredient in Gynoflor E is estriol, which is the natural female sex hormone. Estriol, even in the very low dose contained in Gynoflora E, ensures restoration of the vaginal epithelium, good blood circulation in it, sufficient thickness, elasticity and its hydration. It is also important for the development of Lactobacilli bacteria in the vagina. Both Lactobacilli bacteria and estriol act locally in the vagina.

The lactose in the vaginal tablets can be quickly fermented by Lactobacilli bacteria into lactic acid. Thus, after the first use of the drug, the reproduction and recolonization of Lactobacilli bacteria begins.

Indications

Vaginitis, Climax, Itching and dryness in the genital area

• To restore the Lactobacillus flora after treatment with certain therapeutic agents (e.g,
• For the treatment of local disorders during and after menopause (vaginal dryness, itching, burning, pain during intercourse) and as a concomitant treatment during systemic hormone replacement therapy;

  For the treatment of vaginal discharge of unknown origin or mild to moderate cases of vaginal infections in which the use of antibiotics or chemotherapeutic agents is not exclusively necessary.

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Active ingredient

Lactobacillus acidophilus lyophilisate, Estriol

Composition

Active substances:

Lactobacillus acidophilus lyophilisate 50 mg (at least 100 million viable bacteria) and estriol 0.03 mg.

Auxiliary substances:

Lactose monohydrate,

Microcrystalline cellulose,

Sodium starch-glycolate,

Magnesium stearate,

sodium phosphate anhydrous bicarbonate.

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How to take, the dosage

To restore a healthy vaginal environment, to treat vaginal discharge and infections: 1-2 vaginal tablets every day for 6-12 days is recommended.

To treat local disorders during and after menopause (dryness in the vagina, itching, burning, pain during intercourse), as a concomitant treatment during systemic hormone replacement therapy: 1 vaginal tablet every day for 6-12 days, after that the preventive dose of 1 vaginal tablet 1-2 days a week.

Inject the vaginal tablet deep into the vagina in the evening before going to bed. It is best to do this lying on your back with your legs slightly bent at the knees. Stop treatment during your period and start again after your period has stopped.

Interaction

Continuing treatment with anti-infective agents (e.g., topical or systemic antibiotics) may decrease the effectiveness of Gynoflora E.

Tell your doctor if you are taking or have recently taken other medications, even ones that were not prescribed to you.

Special Instructions

If you experience unexpected vaginal bleeding, treatment should be stopped, and your doctor should find out the cause of the bleeding.

Do not use vaginal showers or gargles during treatment with Gynoflor E. Gynoflor E contains components that do not completely break down, and residues of the tablet may sometimes be found on underwear. The effectiveness of the drug is not affected.

In isolated cases, if the vagina is very dry, the vaginal tablet may not dissolve and come out of the vagina in the primary form. In this case, the treatment is not optimal, although it does not harm the vagina. To prevent such cases, the pill can be moistened with a small amount of plain water before insertion.

Pads should be used during treatment with Gynoflor E.

Contraindications

• High sensitivity to cetirizine, hydroxyzine or piperazine derivatives as well as other drug components.
• Terminal stage of renal failure (creatinine clearance < 10 ml/min).
• Children under 6 years of age (for this dosage form).
• Pregnancy.
• Hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption syndrome.

With caution

In patients:

• with chronic renal insufficiency (with creatinine clearance > 10 ml per min requires dosing regimen adjustment);
• elderly (with age-related decrease in glomerular filtration);
• with epilepsy and with increased seizure readiness;
• with predisposing factors to urinary retention (see section “Special Indications.
• when breastfeeding

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Side effects

A mild burning or hot sensation; redness and itching.

Pregnancy use

Experience with Gynoflor E during pregnancy has shown no evidence of adverse effects on pregnancy or fetal health of the newborn child.

The active ingredients, Lactobacillus acidophilus and estriol, are naturally found in the vagina, and after using Gynoflor, levels of both substances do not exceed those of healthy women.

In this way, Gynoflor E can be used during pregnancy. As with the use of any other medication during pregnancy, consult your doctor.

Gynoflor E can be used during lactation.