Guttasil, tablets 7.5 mg 30 pcs

Preparing for diagnostic procedures, Anal fissures, Hemorrhoids, Constipation

Constipation or cases that require the facilitation of defecation (hemorrhoids, proctitis, anal fissures, preparing for surgery, instrumental and radiological examinations).

Active ingredient

Sodium picosulfate

Composition

1 tablet . sodium picosulfate 7.5 mg

Supplementary substances:

sorbitol 460 mg,

sodium methyl paraoxybenzoate 2.0 mg,

Hydrochloric acid 1 M to pH 6.0-7.0,

water d/i to 1 ml.

How to take, the dosage

Internal, overnight (in order to have stools the next morning).

Interaction

Electrolyte imbalance may lead to decreased tolerance to cardiac glycosides.

Diuretics or GCS may increase the severity of hypokalemia caused by high-dose administration of Guttasil.

Concurrent treatment with antibiotics may decrease the laxative effect of the drug.

Special Instructions

Like other laxatives, Guttasil should not be taken daily for a long time. If daily use of laxatives is necessary, the cause of constipation should be investigated. Prolonged use of laxatives may cause electrolyte imbalance and hypokalemia, and may also lead to addiction and constipation due to the ricochet effect.

Guttasil is effective in relieving constipation in cancer patients receiving high doses of opioids.

The drug contains sorbitol, so it is not recommended for patients with rare hereditary fructose intolerance.

Impact on the ability to drive and operate machinery.

In therapeutic doses the drug does not affect the ability to drive vehicles and operate other mechanisms.

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Contraindications

• high sensitivity to sodium picosulfate and other drug components;
• intestinal obstruction;
• acute inflammatory bowel disease and acute diseases of the abdominal cavity (including. acute appendicitis, non-specific ulcerative colitis, peritonitis);
• acute abdominal pain accompanied by nausea and vomiting, which may indicate acute inflammatory diseases, severe dehydration;
• pregnancy (first trimester);
• lactation period.

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Side effects

Skin disorders: skin rash, urticaria, itching.

Water-electrolyte balance: loss of potassium, sodium and other electrolytes, possible development of dehydration.

Digestive system disorders: dyspeptic complaints, vomiting, nausea, abdominal cramps and pain, diarrhea, flatulence, pain in the stomach and anus area, increased intestinal motility, which improve with reduction of the drug dose.

Immune system disorders: allergic reactions, angioedema.

CNS disorders: headache, increased fatigue, drowsiness, seizures.

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Overdose

Symptoms:

High doses of Guttasil may cause liquid defecation, abdominal cramps (colic), and clinically significant water-electrolyte imbalances (hypokalemia, loss of other electrolytes and fluid) and ischemia of the colonic mucosa. Prolonged overdose leads to development of chronic diarrhea and abdominal pain, hypokalemia, secondary hyperaldosteronism, renal damage and development of nephrolithiasis, metabolic alkalosis, hypokalemia and muscle weakness as a result of hypokalemia are possible.

Treatment:

Gastric lavage, prescription of enterosorbents (activated carbon), symptomatic treatment (correction of water-electrolyte balance, administration of antispasmodics).

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Similarities

Regulax Picosulfate, Guttalax, Slabilen, Slabicap, Picodinar