Glucosamine, 750 mg 60 pcs

Pharmacotherapeutic group: tissue repair stimulator.
ATC code: M01AX05

Pharmacological properties

Glucosamine helps to prevent the destruction of cartilage, stimulates the restoration of cartilage tissue, has anti-inflammatory and analgesic effects, normalizes the production of joint fluid. Improves joint mobility, reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs).

Pharmacokinetics

Gastrointestinal absorption 90%, bioavailability 25%, elimination half-life – 70 hours

Indications

Osteoarthrosis of peripheral joints and spine, osteochondrosis.

Pharmacological effect

Pharmacotherapeutic group: tissue repair stimulator.
ATX code: M01AX05

Pharmacological properties

Glucosamine helps prevent cartilage destruction, stimulates the restoration of cartilage tissue, has anti-inflammatory and analgesic effects, and normalizes the production of intra-articular fluid. Improves joint mobility, reduces the need for non-steroidal anti-inflammatory drugs (NSAIDs).

Pharmacokinetics

Absorption in the gastrointestinal tract 90%, bioavailability 25%, half-life – 70 hours

Special instructions

It is not recommended for children under 12 years of age due to the lack of scientific data for this category of patients. The risk of allergic reactions increases with seafood intolerance. When using the drug in patients with impaired glucose tolerance, with severe liver and kidney failure, medical supervision is required.

Impact on the ability to drive vehicles and machinery

The effect of glucosamine on the ability to drive a car and operate machinery has not been studied. However, based on pharmacodynamic properties and overall safety profile, it seems unlikely that glucosamine has such an effect.

Active ingredient

Glucosamine

Composition

Each tablet contains the active ingredient: glucosamine sulfate sodium chloride – 942.1 mg, in terms of glucosamine sulfate – 750.0 mg.

Excipients (core):
microcrystalline cellulose – 320.0 mg,
colloidal silicon dioxide – 10.0 mg,
croscarmellose sodium – 44.9 mg,
purified water – 20.0 mg,
povidone-K25 – 49.0 mg,
magnesium stearate – 14.0 mg.

Excipients (shell):
hypromellose – 22.8 mg,
macrogol-4000 – 5.6 mg,
titanium dioxide – 11.6 mg.

Pregnancy

The use of the drug during pregnancy and breastfeeding is contraindicated due to the lack of scientific clinical data in this category of patients.

Contraindications

Hypersensitivity to the active substance and other components of the drug, severe chronic renal failure. It is not recommended to prescribe the drug during pregnancy and breastfeeding, as well as in childhood (up to 12 years) due to the lack of scientific clinical data in this category of patients.

With caution

Side Effects

Dysfunction of the gastrointestinal tract (epigastric pain, flatulence, diarrhea, constipation, nausea), allergic skin reactions (urticaria, itching, erythema), nervous system reactions (headache, drowsiness).

Interaction

Increases the absorption of tetracyclines, reduces the effect of semisynthetic penicillins, chloramphenicol. Enhances the effect of coumarin anticoagulants. The drug is compatible with paracetamol, NSAIDs and glucocorticosteroids.

When used together with NSAIDs, it enhances the anti-inflammatory and analgesic effect of the latter.

Overdose

Symptoms: cases of overdose are unknown. Treatment: gastric lavage, symptomatic therapy.

Storage conditions

In a place protected from light at a temperature not exceeding 25 °C.
Keep out of the reach of children.

Shelf life

3 years.

Manufacturer

Ozon, Russia