Furamag, capsules 25 mg 30 pcs

Furamag is a broad-spectrum antimicrobial agent belonging to the group of nitrofurans.

Resistance to Furamag develops slowly and does not reach a high degree.

Active against Gram-positive cocci: Streptococcus spp., Staphylococcus spp.; Gram-negative bacilli: Escherichia coli, Salmonella spp., Shigella spp., Proteus mirabilis, Klebsiella spp, Enterobacter spp.; protozoa: Lamblia intestinalis and other microorganisms resistant to antibiotics.

With regard to Staphylococcus spp, Escherichia coli, Aerobacter aerogenes, Leuconostoc citrovorum, Proteus mirabilis, Proteus morganii Furamag® is more active than other nitrofurans.

Against most bacteria, the bacteriostatic concentration is 1:100,000 to 1:200,000. Bactericidal concentration is about 2 times higher.

Under the influence of nitrofurans in microorganisms the respiratory chain and tricarboxylic acid cycle (Krebs cycle) is suppressed and other biochemical processes of microorganisms are inhibited, resulting in destruction of their shell or cytoplasmic membrane.

As a result of the action of nitrofurans microorganisms release fewer toxins, so that improvement of the overall condition of the patient is possible even before a pronounced suppression of microflora growth. Nitrofurans activate the body’s immune system: they increase the complement titer and the ability of leukocytes to phagocytize microorganisms. Furazidine in therapeutic doses stimulates leukopoiesis.

Indications

Infections caused by susceptible microorganisms:

– urogenital infections (acute cystitis, urethritis, pyelonephritis);

– gynecological infections;

– Skin and soft tissue infections;

– Severely infected burns;

– For prophylactic purpose during urologic surgeries (including cystoscopy, cystic and percutaneous surgeries).Cystoscopy, catheterization).

Active ingredient

Composition

Furazidine (in the form of potassium salt) 25 mg.

Excipients:

magnesium carbonate basic,

potassium carbonate,

talc.

How to take, the dosage

The preparation should be taken orally after meals.

Adults are prescribed 50-100 mg 3 times a day.

Children over 3 years of age are prescribed 25-50 mg (not more than 5 mg/kg of body weight) 3 times a day.

The course of treatment is 7-10 days. If the treatment course should be repeated a break should be made during 10-15 days.

For prophylaxis of infection (including during urologic operations, cystoscopy, catheterization) the drug is prescribed to adults by 50 mg and to children – by 25 mg once 30 minutes before the procedure.

In case the drug is missed the next dose should be taken at the usual time. Do not take a double dose to compensate for the missed dose.

Interaction

Furamag® should not be used simultaneously with ristomycin, chloramphenicol, sulfonamides (increased risk of hematopoiesis inhibition).

It is not recommended that drugs that can acidify the urine (including ascorbic acid, calcium chloride) be administered simultaneously with nitrofurans.

Special Instructions

To reduce the likelihood of side effects Furamag® should be drunk with plenty of fluid.

The drug should be discontinued if side effects occur (toxic effects are more common in patients with reduced renal excretory function).

The patient must inform the physician of any side effects that occur during treatment with the drug.

The patient is advised to refrain from drinking alcoholic beverages during treatment, as there may be increased side effects.

The effect of Furamag on driving and operating machinery has not been noted.

Contraindications

– severe chronic renal insufficiency;

– pregnancy;

– lactation (breast-feeding) period;

Side effects

The digestive system: rarely – nausea, vomiting, loss of appetite, liver function disorders.

CNS and peripheral nervous system disorders: rarely – headache, dizziness, polyneuritis.

Allergic reactions: rare – skin rash (including papular rash).

Furamag® is slightly toxic.

Overdose

Symptoms: neurotoxic manifestations, ataxia, tremor.

Treatment: you should drink plenty of fluids. Antihistamines (diphenhydramine) are used to relieve acute symptoms. Vitamins (thiamine bromide) may be prescribed to prevent neuritis.

Similarities