Fungoderil, 1% 15 ml

Pharmacotherapeutic group: Antifungal agent

Pharmacodynamics

Naphtifine is an antifungal agent for external use, belonging to the class of allilamines. The mechanism of action is related to inhibition of squalene-2,3-epoxidase, which reduces the formation of ergosterol, a component of the cell wall of the fungus.

Active against dermatophytes such as Trichophyton, Epidermophyton, Microsporum, molds (Aspergillus spp.), yeasts (Candida spp., Pityrosporum) and other fungi (such as Sporothrix schenckii). Against dermatophytes and aspergillus naphthifin acts fungicidal.

Against yeast fungi naphthifin has fungicidal or fungistatic activity depending on the microorganism strain. It has antibacterial activity against Gram-positive and Gram-negative microorganisms that may cause secondary bacterial infections. It has anti-inflammatory effect, which contributes to the rapid disappearance of inflammatory symptoms, especially itching.

Pharmacokinetics

Indications

Active ingredient

Composition

How to take, the dosage

Externally.

In case of skin lesions

Apply once a day to the affected skin surface and its surrounding areas (about 1 cm of healthy skin around the edges of the affected area) after thoroughly cleaning and drying them.

The therapy duration is 2-4 weeks in dermatomycosis (up to 8 weeks if necessary); 4 weeks in candidiasis.

In case of nail lesions

Apply on the affected nail. Before the first application, remove the affected part of the nail with a pair of scissors or a nail file as much as possible.

The duration of therapy for onychomycosis is up to 6 months.

To prevent recurrence, treatment should be continued for at least 2 weeks after clinical symptoms have disappeared.

Special Instructions

The drug is not intended for use in ophthalmology. Avoid contact of the drug with the eyes.

Course treatment is required to achieve therapeutic effect. The drug is effective in the treatment of mycosis affecting areas of the skin with hyperkeratosis and also in hair growth areas.

Synopsis

Contraindications

Hypersensitivity to naphthyphine or other ingredients of the drug; pregnancy and breastfeeding (safety and effectiveness of use have not been established), application to the wound surface.

Childhood (experience with clinical use limited).

Side effects

Pregnancy use

Similarities