Forlax, 4 g 20 pcs.

Forlax is a laxative.

Pharmacodynamics

The high molecular weight compound macrogoal 4000 is a linear polymer that retains water molecules through hydrogen bonds. This increases the volume of intestinal contents after oral administration.

The volume of unabsorbed fluid in the intestinal lumen supports the laxative effect of the solution.

Pharmacokinetics

Pharmacokinetic data confirm that macrogoal 4000 undergoes neither gastrointestinal resorption nor biotransformation when taken orally.

Indications

Active ingredient

Composition

active ingredient:

macrogol 4000 – 4 g,

Auxiliary substances:

Orange and Grapefruit Fragrance* – 60.0

Sodium saccharinate (E954) – 6.8

* Orange oil, grapefruit oil, concentrated orange juice, citral, acetic aldehyde, linalool, ethyl butyrate, alpha terpineol, octanal, cis-3-hexenol, maltodextrin, acacia gum, sorbitol (E420), sulfur dioxide (E220), butylhydroxyanisole (E320).

How to take, the dosage

Interaction

Special Instructions

The data on the effectiveness of therapy in children under 2 years of age are limited.

The treatment of constipation with medication is recommended only as an adjunct to a healthy lifestyle and diet, such as:

– increasing fluid and fiber intake,

– adequate physical activity that helps restore the motility of the digestive tract.

Organic gastrointestinal disorders should be ruled out prior to initiation of therapy.

Contraindications

Side effects

The adverse reactions listed in the table below have been reported in clinical trials involving 147 children aged 6 months to 15 years and during post-registration use.

In general, adverse reactions were mild and transient and mostly involved the gastrointestinal systems.

The frequency of adverse drug reactions was determined according to the following grading: very common (≥1/10); common (≥1/100, < 1/10); infrequent (≥1/1000, < 1/100), rare (≥1/10000, < 1/1000), very rare (< 1/10000), frequency not determined (cannot be estimated from available data).

Gastrointestinal disorders:

Often – Abdominal pain, Diarrhea*

Infrequent – Vomiting , Bloating, Nausea

Immune system disorders

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Frequency not established – Hypersensitivity reactions (anaphylactic shock, angioedema, urticaria, rash, itching).

* Diarrhea may cause perianal irritation.

Overdose

Diarrhea may occur, which stops when the dose of the drug is reduced or cancelled.

Intensive diarrhea or vomiting may cause an imbalance of the electrolyte balance, which will require correction.

There have been reports of perianal inflammation and irritation and fecal incontinence when large volumes (4-11 liters) of polyethylene glycol have been used for colon cleansing prior to colonoscopy.

Pregnancy use

Pregnancy Experiments in rats and rabbits have shown that Macrogol 4000 has no teratogenic effect.

Pregnant women should exercise caution when prescribing Forlax to pregnant women because of the paucity of data on the use of Forlax in pregnant women.

Lactation It is not known whether the drug passes into the mother’s milk. Because macrogol 4000 is not absorbed, Forlax can be taken during lactation.

Similarities