Flucinar, gel 0.025% 15 g
€12.42 €10.35
Flucinar is a synthetic GKS for external use. It has anti-inflammatory, antipruritic, anti-allergic, anti-exudative effects.
The mechanism of anti-inflammatory action is not fully understood. Fluocinolone acetonide inhibits the synthesis of prostaglandins and leukotrienes by inhibition of phospholipase A2 activity and reduces the release of arachidonic acid from phospholipids of the cell membrane. It prevents local allergic reactions in the skin. Antiexudative effect is caused by the vasoconstrictor action.
Easy penetration into the skin through the stratum corneum. It is not biotransformed in the skin and it accumulates in the stratum corneum. Fluociolone acetonide is detectable in the skin even after 15 days after topical application.
When used topically, fluocinolone acetonide may be slightly absorbed into the systemic bloodstream and cause general effects. The absorbed part is biotransformed mainly in the liver and is excreted from the body as compounds with glucuronic acid and in small amounts in unbound form. It is excreted mainly with urine and slightly with bile.
Absorption of fluocinolone acetonide is more pronounced when it is applied to the face and affected areas of the skin, as well as when using occlusive dressings. In addition, absorption of the drug increases when it is used frequently and when applied to large areas of skin. Absorption of the drug in children is more pronounced than in adults.
Indications
Flucinard in gel form is indicated for the treatment of hairy skin, as well as for patients who do not tolerate the drug in the form of an ointment because of the components of the ointment base.
Active ingredient
Composition
1 g of the gel contains:
The active ingredient:
fluocinolone acetonide 0.25 mg;
Associates:
Propylene glycol;
Ethanol;
dinatrium salt of ethylenediaminetetraacetic acid (trilon B);
citric acid;
Methyl hydroxybenzoate;
propyl hydroxybenzoate;
carbopol 940;
triethanolamine;
purified water.
How to take, the dosage
Externally. Apply to the affected surface, rubbing gently, 1-2 times a day, not more than 2 g/day. In psoriasis it is possible to use occlusive dressing. Course duration is not more than 1-2 weeks. On the skin of the face it is used very cautiously and for not more than 1 week.
Children over 2 years of age – with caution, only once a day, on small areas of skin.
Contraindications
Side effects
Skin and subcutaneous fatty tissue atrophy, lupus-like syndrome with a mild course, the appearance or exacerbation of symptoms of squamous capitis, disorders of epithelialization, delayed wound and ulcer healing, petechiae, steroid purpura, stretch marks, hirsutism, female pattern baldness, maculopapular skin rash.
Overdose
Symptoms: if the dosing regimen is not followed (prolonged use of the drug on large areas of skin) systemic side effects of the drug such as increased BP, edema, immunosuppressive effects are possible.
Treatment: discontinuation of the drug.
Similarities
Weight | 0.024 kg |
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Shelf life | 3 years |
Conditions of storage | At a temperature not exceeding 25 °C. Do not freeze. |
Manufacturer | Jelfa Pharmzavod, Poland |
Medication form | gel for external use |
Brand | Jelfa Pharmzavod |
Other forms…
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