Flogardin, 60 mg 10 pcs.

Pharmacotherapeutic group: antiviral immunostimulant – inducer of interferon formation.

TAC code: J05AX

Pharmacological properties

Pharmacodynamics

Low molecular weight synthetic interferon inducer that stimulates formation of all types of interferons in the body (alpha, beta, gamma and lambda). The main producers of interferon in response to tiloron administration are intestinal epithelial cells, hepatocytes, T-lymphocytes, neutrophils and granulocytes. After oral administration maximum production of interferon is determined in the sequence
intestine – liver – blood in 4-24 hours. Tiloron has immunomodulatory and antiviral effects.

Pharmacokinetics

After oral administration, it is rapidly absorbed from the gastrointestinal tract. Bioavailability is 60%.

About 80% of tiloron is bound to plasma proteins.

Tilorone is taken out practically unchanged through intestine (70%) and kidneys (9%). The elimination half-life (T_1/2) is 48 hours. Tiloron is not biotransformed and does not accumulate in the body.

Indications

Active ingredient

Composition

One tablet

How to take, the dosage

Ingestion, after meals.

In uncomplicated forms of influenza and acute respiratory infections – 60 mg per day on days 1, 2 and 4 from the start of treatment. The course dose is 180 mg (3 tablets for the course of treatment).

When treating influenza and other acute respiratory viral infections, if symptoms persist for more than 4 days, a physician should be consulted.

Interaction

Compatible with antibiotics and drugs of traditional treatment of viral and bacterial diseases. No clinically significant interaction of tiloron with antibiotics and drugs of traditional treatment of viral and bacterial diseases was found.

Special Instructions

Impact on driving, operating machinery

Flogardin®

does not affect the ability to drive vehicles and engage in other potentially dangerous activities requiring increased concentration and rapid psychomotor reaction.

Synopsis

Circular biconvex orange film-coated tablets. On the cross section the core is orange in color; slight darker or lighter stains are allowed.

Contraindications

Side effects

Allergic reactions, dyspepsia, and transient chills may occur. If any of the side effects mentioned in the instructions worsen, or if you notice any other side effects not mentioned in the instructions, tell your doctor.

Overdose

There are no known cases of overdose of Flogardin®.

Pregnancy use

The use of the drug Flogardin® in pregnancy is contraindicated.

If it is necessary to prescribe the drug in lactation, breastfeeding should be stopped.

Similarities