Fibro-Vein, 3%, 2 ml, 5 pcs.

The drug Fibro-Vein has a venosclerosing effect, it has surface-active properties.

Injection of the drug into the lumen of the varicose vein causes irritation of the vessel intima with subsequent fibrosis, adhesion of the vein walls and its obliteration.

It has no noticeable effect on the functions of the central and peripheral nervous system, cardiovascular system, renal and hepatic function, biochemical parameters of blood and urine.

In contact with perivascular tissues it has an irritating effect.

Indications

Active ingredient

Composition

Active ingredient:

Sodium tetradecyl sulfate 3 mg.

How to take, the dosage

Fibro-Vein is injected intravenously, into the lumen of an isolated segment of an empty superficial vein with immediate prolonged compression (application of a compression bandage).

The dosage is determined according to the size of the vein to be sclerosed; the usual dose is 1 ml (no more) per site. For Fibro-Vein 3%, the maximum single dose is 4 ml.

If necessary, additional injections are performed after a 2-week break.

Interaction

Pharmaceutically incompatible with heparin. It is not recommended to combine with oral contraceptives (especially anti-ovulatory).

Special Instructions

1. Fibro-Vein should be used by physicians proficient in sclerotherapy techniques. Valve insufficiency and the condition of deep veins should be properly evaluated.
2. Vein sclerosing should be performed with caution when absolute certainty of the patency of deep and communicating veins of the lower limbs.
3. The patient’s allergic history should be known prior to treatment. It is possible to give 0,25-0,5 ml of Fibro-Vein 24 hours before the treatment to detect possible allergic reactions.
4. Caution should be exercised when treating patients with peripheral atherosclerosis, Buerger’s disease.
5. The drug should be injected particularly carefully in the area above and behind the medial ankle, because the posterior tibial artery is located there.
6. Avoid extravasal (para-venous) and intraarterial administration.
7. Do not use the drug if precipitation or color change of the solution.
8. Precipitate formation is possible in the solution which dissolves upon heating.
9. For prevention of relapse after treatment the patients are recommended to wear elastic stockings.

Contraindications

Side effects

Local reactions: skin hyperemia, slight soreness or burning sensation at the injection site is possible.

Allergic reactions: Rare.

Pregnancy use

Fibro-Vein is contraindicated in pregnancy and lactation