Ezlor Solution Tablets, 5 mg 10 pcs

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Indications

– Allergic rhinitis (elimination or relief of sneezing, nasal congestion, nasal mucus secretion, nasal itching, palate itching, itching and red eyes, lacrimation);

– Urticaria (reduction or elimination of skin itching, rash).

Active ingredient

Composition

Active ingredient:

desloratadine – 5.0 mg.

Additional Ingredients:

calcium hydrophosphate dihydrate – 170.0 mg;

microcrystalline cellulose – 50.0 mg;

Sodium carboxymethyl starch – 6.0 mg;

aspartame – 5.0 mg;

magnesium stearate – 2.4 mg;

colloidal silicon dioxide – 1.6 mg.

How to take, the dosage

Ingestion, regardless of the time of the meal. The tablet should be dissolved in a small amount of water (10-50 ml or ¼ cup), the solution should be stirred before use.

Adults and adolescents over 12 years of age – 1 tablet (5 mg) once a day.

In children 6 to 12 years of age, 1 tablet (2.5 mg) once daily.

In children from 1 to 6 years of age, 1 ½ tablet (1.25 mg to ½ tablet with a dose of 2.5 mg) once daily.

In case of seasonal (intermittent) allergic rhinitis (with symptoms lasting less than 4 days per week or less than 4 weeks per year), the course of the disease should be evaluated. If symptoms disappear, the drug should be stopped; if symptoms reappear, the drug should be resumed.

In case of year-round (persistent) allergic rhinitis (with symptoms lasting more than 4 days per week or more than 4 weeks per year), the drug should be taken for the duration of allergen exposure.

The duration of therapy with the drug should be determined by consulting your doctor.

Interaction

Special Instructions

In the recommended dose the drug does not affect the ability to drive vehicles or operate mechanisms.

The potential for side effects such as dizziness and somnolence must be considered. If the described adverse events occur, the following activities should be avoided.

Contraindications

– Hypersensitivity to desloratadine, other components of the drug or to loratadine,

– pregnancy and breastfeeding,

– children under 1 year of age,

– phenylketonuria.

Side effects

The frequency of side effects is classified according to the World Health Organization recommendations: very frequently – at least 10%; frequently – at least 1%, but less than 10%; infrequently – at least 0.1%, but less than 1%; rarely – at least 0.01%, but less than 0.1%; very rarely – less than 0.01%; the frequency is unknown (according to available data it is impossible to determine the frequency).

Immune system disorders: very rare – itching, rash, including urticaria, angioedema, dyspnea, anaphylaxis.

As to the central nervous system: often – headache, insomnia (in children under 2 years); very rarely – dizziness, somnolence, insomnia, psychomotor hyperactivity, seizures, hallucinations.

Cardiovascular system disorders: very rarely – tachycardia, palpitations, prolongation of QT interval.

Gastrointestinal tract: often – dry mouth, diarrhea (in children under 2 years of age); very rarely – nausea, vomiting, dyspepsia, diarrhea, abdominal pain, increased “liver” enzymes activity, increased concentration of bilirubin, hepatitis.

Skeletal and connective tissue disorders: very rarely – myalgia.

Skin and subcutaneous tissue disorders: very rare – photosensitization.

Others: frequent – increased fatigue, fever (in children younger than 2 years); frequency unknown – asthenia.

Post-registration period

Children: frequency unknown – prolongation of the QT interval, arrhythmia, bradycardia.

If any of the side effects listed in the instructions worsen, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose

Symptoms: Taking a dose 5 times the recommended dose did not result in any symptoms. In clinical trials, daily use in adults and adolescents in doses up to 20 mg for 14 days was not accompanied by statistically or clinically significant changes in the cardiovascular system.

In a clinical and pharmacological study, the use of desloratadine at a dose of 45 mg daily (9 times the recommended dose) for 10 days did not cause QT interval prolongation and was not accompanied by the occurrence of serious side effects.

Pregnancy use

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