Eskusan, drops 20 ml

Escusan is a phytopreparation used for disorders of the venous circulation.

It has anti-exudative and venotonic effect. It was found that horse chestnut seed extract reduces the concentration of lysosomal enzymes, resulting in decreased breakdown of mucopolysaccharides in the capillary walls.

Escusan reduces vascular permeability by preventing filtration of low molecular weight proteins, electrolytes and water into the intercellular space.

Indications

Chronic venous insufficiency class I–III according to the CEAP classification: varicose veins, swelling, cramps in the calf muscles, a feeling of heaviness in the legs.

Pharmacological effect

Aescusan is a herbal medicine used for venous circulation disorders.

It has an antiexudative and venotonic effect. It has been established that horse chestnut seed extract reduces the concentration of lysosomal enzymes, resulting in a decrease in the breakdown of mucopolysaccharides in the area of ​​capillary walls.

Aescusan reduces vascular permeability, preventing the filtration of low molecular weight proteins, electrolytes and water into the intercellular space.

Special instructions

Escusan contains 31% ethanol. If the recommended dosages are observed, up to 0.128 g of ethanol enters the body with each dose of the drug; the maximum daily dose of the drug contains up to 0.384 g of ethanol.

During long-term storage of drugs (liquid dosage forms) based on medicinal plant raw materials, the solution may become cloudy and sediment may form, which does not affect the quality of the drug.

Impact on the ability to drive vehicles and operate machinery.

During the period of use of the drug, care should be taken when performing potentially hazardous activities that require increased attention and speed of psychomotor reactions (driving a car and other vehicles, working with moving mechanisms, working as a dispatcher and operator).

Active ingredient

Thiamine, Escin

Composition

100 g of oral solution contains:

Active ingredients:

horse chestnut seed extract dry (Hippocastani extractum siccum normatum) 5–7:1 4.725 g (extractant – ethanol 60% v/v), thiamine hydrochloride 0.5 g,

Excipients:

ethanol 96% – 26.4 g;

purified water – 67.675 g;

lactose monohydrate – 0.432 g;

colloidal silicon dioxide – 0.243

Contraindications

hypersensitivity to the components of the drug Aescusan;
liver diseases;
lactose intolerance, lactase deficiency, glucose-galactose malabsorption;
children’s age (up to 12 years).

With caution: alcoholism; traumatic brain injury; brain diseases; children’s age (over 12 years).

Side Effects

Allergic reactions are possible,
irritation of the gastrointestinal mucosa,
headaches,
dizziness.

Interaction

The effect of thiamine is reduced when used simultaneously with sulfite-containing infusion solutions.

Fluorouracil, vinblastine, bleomycin, cisplatin interfere with the absorption of vitamin B1. Penicillamine and isoniazid reduce the effectiveness of vitamin B1, increasing its excretion.

Overdose

Symptoms: a feeling of heaviness in the epigastric region may occur.

Treatment: symptomatic. The drug should be discontinued.

Storage conditions

At 8–25 °C

Shelf life

3 years

Manufacturer

Pharma Wernigerode GmbH, Germany