Enterosgel, paste 225 g
€13.36 €11.13
Pharmacological group
Entherosorbent.
Pharmacological action
Entherosgel has a porous structure of silicone matrix (molecular sponge) of hydrophobic nature, which is characterized by sorption action against only medium molecular weight toxic metabolites (m.m. from 70 to 1000).
Pharmacodynamics
Entherosgel has pronounced sorption and detoxification properties.
In the lumen of the gastrointestinal tract the preparation binds and removes from the body endogenous and exogenous toxic substances of various origins, including bacteria and bacterial toxins, antigens, food allergens, drugs and poisons, heavy metals and alcohol.
The preparation also sorbs some products of the body’s metabolism, including excessive bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicosis. Enterosgel does not reduce absorption of vitamins and microelements; it helps restore disturbed intestinal microflora and does not affect intestinal motility.
Pharmacokinetics
The drug is not absorbed in the gastrointestinal tract and is eliminated unchanged within 12 hours.
Indications
Diathesis, Common acne (vulgar), Nausea, Toxicosis of pregnant women, Hepatitis, Urticaria, Dermatitis, Intestinal infections, Hangover, Kidney disease, Colic, Psoriasis, Salmonellosis, Vomiting, Obesity, Poisoning, Diarrhea, Dysbacteriosis
Enterosgel is used in adults and children as a detoxifying agent:
- acute and chronic intoxication of various origins;
- acute poisoning with potent and poisonous substances, including drugs and alcohol, alkaloids, salts of heavy metals;
- pyo-septic diseases accompanied by severe intoxication, in the treatment;
- meteorism;
- food and drug allergies;
- hyperbilirubinemia (viral hepatitis) and hyperazotemia (chronic renal failure);
- and to prevent chronic intoxication.for the prevention of chronic intoxication in workers in hazardous industries (occupational intoxication by chemical agents of polytropic action, xenobiotics, incorporated radionuclides, compounds of lead, mercury, arsenic, petroleum products, organic solvents, nitrogen oxides, carbon, fluorides, salts of heavy metals).
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Active ingredient
Polymethylsiloxane polyhydrate
Composition
100 g of paste for oral administration contains:
Active substances:
Polymethylsiloxane polyhydrate (non-linear polycondensation product of 1,1,3,3-tetrahydroxy-1,3-dimethyldisiloxane polyhydrate) 70 g.
Auxiliary substances:
Purified water – 30 g.
How to take, the dosage
Dosage and administration
Ingestion, 1-2 hours before meals or other drugs, with water.
It is recommended to take with water or dilute the dose in half a glass of water before taking.
Dosing regimen for different age groups
- Dosage for adults is 1 sachet or 22.5 g (1.5 tablespoons) 3 times daily. The daily dose is 67.5 g (3 packets);
- Dosage for children aged 5 to 14 years – 15 g (1 tablespoon) 3 times a day. Daily dose – 45 grams (2 packets);
- Dosage for children under 5 years of age – 7.5 grams (0.5 tablespoons) 3 times a day. The daily dose is 22.5 g (1 sachet).
- Dosage for infants – it is recommended that 2.5 g (0.5 tsp) of the drug be mixed in triple volume of breast milk or water and given before each feeding (6 times a day).
Dosing regimen depending on symptoms
For the prevention of chronic intoxication, one bag or 1.5 tablespoons (22.5 g) 2 times daily for 7-10 days, monthly.
Application in acute diarrhea:
- Dosage for adults and children from 5 years: the initial dose is 2 packets or 45 g (3 tbsp) for adults and 1 packet or 22.5 g (1.5 tbsp) for children, subsequently take 1 packet or 22.5 g (1.5 tbsp) after each act of defecation in case of liquid stool.
- Dosage for children under 5 years of age: Starting dose is 1 tablespoon (15 g), then take 1.5 teaspoon (7.5 g) after each act of defecation in case of loose stools.
After stopping diarrhea, take the drug for 5 days at the usual dosage.
In severe intoxication during the first three days, the dose of the drug may be doubled.
The duration of treatment in acute intoxications is 3-5 days, in chronic intoxications and allergic conditions – 2-3 weeks.
Repeated course – upon the doctor’s recommendation.
Interaction
It is possible to reduce absorption of other drugs when taking Enterosgel at the same time.
Special Instructions
Precautionary measures when taking the drug
Entherosgel can be used in combination therapy with other medicinal products with observance of the rule of separate time of taking – 1-2 hours before or after taking other drugs.
The results of recent published clinical trials (see Clinical guidelines “Obstetrics and gynecology”, 4th edition, revised and supplemented, M. GETAR-Media, 2014) allow us to recommend Enterosgel as part of the complex therapy of patients with endometritis and gestational pyelonephritis.
Entherosgel (polymethylsiloxane polyhydrate) has pronounced sorption and detoxification properties. In the gastrointestinal tract polymethylsiloxane polyhydrate binds and removes endogenous and exogenous toxic substances of various nature including bacteria and bacterial toxins, antigens, food allergens, metabolites of medicines and salts of heavy metals. The drug also sorbs metabolic products of the body, including excess bilirubin, urea, cholesterol and lipid complexes, as well as metabolites responsible for the development of endogenous toxicity. Polymethylsiloxane polyhydrate does not reduce absorption of vitamins and microelements, promotes restoration of disrupted intestinal microflora and does not affect its motor function.
Interaction with alcohol
There are no data on the interaction with alcohol.
Prescription conditions from pharmacies
The drug is approved for over-the-counter use.
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Contraindications
The contraindication to the use of Enterosgel is:
- high sensitivity to the drug;
- gastrointestinal bleeding;
- intestinal obstruction.
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Side effects
When the drug is used, the following may occur:
- rejection of Enterosgel;
- nausea;
- constipation;
- diarrhea.
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Overdose
Cases of overdose of Enterosgel have not been identified.
Pregnancy use
Enterosgel is not contraindicated in pregnancy and during lactation (breastfeeding).
In children it is possible to use from infancy.
Similarities
EnteroZoo
Weight | 0.285 kg |
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Shelf life | 3 years |
Conditions of storage | At a temperature of at least 4 °C |
Manufacturer | Silma TNK LLC, Russia |
Medication form | oral paste |
Brand | Silma TNK LLC |
Other forms…
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