Enterofuryl, capsules 100 mg 30 pcs

Enterofuryl® is a broad-spectrum antimicrobial drug that has no systemic action and is used for treatment of diarrhea of infectious etiology. Enterofuryl® contains the active substance nifuroxazide, a drug of 5-nitrofuran derivatives group.

The drug has a bactericidal and bacteriostatic effect against most pathogens of acute intestinal infections. Antimicrobial action of nifuroxazide is dose-dependent: thus, low and medium doses of the drug have a bacteriostatic effect against pathogenic microflora, and high – bactericidal.
The bacteriostatic mechanism of action of the drug is associated with inhibition of dehydrogenase enzyme activity, which leads to disruption of the normal course of synthesis of vital compounds in the cell of the microorganism. Thus, due to the effect of nifuroxazide on a microorganism cell a disruption of the respiratory chain and inhibition of tricarboxylic acid cycle is observed.

Besides, Enterofuryl® inhibits protein synthesis in a microorganism cell and inhibits other biochemical processes in a bacterial cell. Thus, the microorganism cell loses its ability to reproduce.

Indications

Active ingredient

Composition

1 capsule contains:

active ingredient:

nifuroxazid 200 mg,

excipients:

sucrose – 71 mg;

corn starch – 68 mg;

MCC – 9 mg;

Magnesium stearate – 2 mg

coating:

gelatin;

titanium dioxide;

iron oxide yellow dye.

How to take, the dosage

Special Instructions

In the treatment of diarrhea, rehydration therapy (oral or intravenous) should be given concomitantly with nifuroxazide therapy according to the patient’s condition and the intensity of the diarrhea.

The use of alcohol during therapy with nifuroxazide is prohibited.

Before prescribing the suspension in infants, it is necessary to rule out congenital deficiency of sucrose digesting enzymes.

Impact on the ability to drive vehicles and operate machinery. The drug does not affect the psychomotor activity and the ability to drive vehicles and operate mechanisms.

Contraindications

Fructose intolerance, glucose-galactose malabsorption syndrome or insufficiency of sucrose and isomaltase. hypersensitivity to nitrofuran derivatives or other components of the drug; children under 3 years of age.

Side effects

Overdose

The drug is not absorbed from the gastrointestinal tract and does not enter the systemic circulation.

The symptoms of overdose are not known. In case of overdose, gastric lavage and symptomatic treatment are recommended.

Pregnancy use

The use of Enterofuryl during pregnancy is possible only in cases when the expected benefits of therapy for a mother exceed the potential risk to the fetus.

Entrofuryl is not absorbed from the gastrointestinal tract and does not enter the systemic circulation, but the drug may be used during lactation only with strict indications, in this case the issue of stopping breastfeeding should be solved.

Similarities