Eluphor, 200 mg capsules 12 pcs

Nifuroxazide is a nitrofuran derivative with antimicrobial activity. Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp.; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp. Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes.
Resistant to nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp, Pseudomonas spp. Supposedly blocks dehydrogenase activity and inhibits respiratory chains, tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell. It does not disturb the balance of intestinal microflora.
In acute bacterial diarrhea it restores intestinal eubiosis. In case of infection with enterotropic viruses it prevents the development of bacterial superinfection.

Pharmacokinetics
After oral administration nifuroxazide is practically not absorbed from the gastrointestinal tract and has no systemic action; 99% of the dose taken remains in the intestine and has its antimicrobial effect there. Nifuroxazide is excreted by the intestine: 20% in unchanged form and the remaining amount of nifuroxazide is chemically altered.

Indications

Acute bacterial diarrhea, occurring without deterioration in general condition, increase in body temperature, or intoxication.

Pharmacological effect

Nifuroxazide is a nitrofuran derivative that has an antimicrobial effect. Highly active against Campylobacter jejuni, Escherichia coli, Salmonella spp., Shigella spp; Clostridium perfringens, Vibrio cholerae, pathogenic Vibrions and Vibrio parahaemolytique, Staphylococcus spp. Weakly sensitive to nifuroxazide: Citrobacter spp, Enterobacter cloacae, Proteus indologenes.
Resistant to nifuroxazide: Klebsiella spp, Proteus mirabilis, Providencia spp., Pseudomonas spp. Presumably blocks the activity of dehydrogenases and inhibits the respiratory chain, the tricarboxylic acid cycle and a number of other biochemical processes in the microbial cell. Does not disturb the balance of intestinal microflora.
In acute bacterial diarrhea, it restores intestinal eubiosis. When infected with enterotropic viruses, it prevents the development of bacterial superinfection.

Pharmacokinetics
After oral administration, nifuroxazide is practically not absorbed from the gastrointestinal tract and does not have a systemic effect; 99% of the dose taken remains in the intestines and exerts its antimicrobial effect there. Nifuroxazide is excreted by the intestines: 20% unchanged, and the remaining amount of nifuroxazide is chemically modified.

Special instructions

When treating diarrhea, rehydration therapy must be carried out simultaneously with nifuroxazide therapy.
In case of bacterial diarrhea with signs of systemic damage (deterioration of general condition, increased body temperature, symptoms of intoxication or infection), you should consult a doctor about the use of systemic antimicrobial drugs.
A daily dose of 800 mg contains 0.023 XE.
Alcohol consumption is prohibited during treatment with Elufor.
If symptoms of an allergic reaction appear (including shortness of breath, rash, itching), you should stop taking the drug and consult a doctor.

Impact on the ability to drive vehicles and machinery

The drug does not affect the ability to drive vehicles and machinery.

Active ingredient

Nifuroxazide

Composition

For 1 capsule:

Contraindications

hypersensitivity to nifuroxazide, nitrofuran derivatives or any excipients of the drug;
children under 3 years of age (for this dosage form);
pregnancy;
sucrase/isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

Side Effects

Allergic reactions (skin rash, urticaria, Quincke’s edema, anaphylactic shock). If any of the side effects indicated in the instructions get worse, or you notice any other side effects not listed in the instructions, tell your doctor.

Interaction

Concomitant use with drugs that cause the development of disulfiram-like reactions and drugs that inhibit the function of the central nervous system is not recommended.
If you are taking other medications (including over-the-counter medications), consult your doctor before using Elufor.

Storage conditions

At a temperature not exceeding 25 °C.
Keep out of the reach of children.

Shelf life

3 years. Do not use the drug after the expiration date.

Manufacturer

Ozon, Russia