Drotaverin-Teva, tablets 40 mg 40 pcs
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Drotaverine is a myotropic antispasmodic. In its chemical structure and pharmacological properties it is similar to papaverine, but has a stronger and longer action.
Decreases influx of ionized calcium into smooth muscle cells due to inhibition of phosphodiesterase and intracellular accumulation of cAMP.
It has a pronounced and long-lasting effect on the smooth muscle of internal organs and blood vessels.
Dilates blood vessels, causes a moderate decrease in blood pressure, increases cardiac output, has some antiarrhythmic effect.
Decreases the tone of the cerebral vessels and increases their blood flow.
It has practically no effect on the autonomic nervous system and does not penetrate into the central nervous system.
Drotaverine has no anticholinergic effect, so unlike cholinolytic antispasmodics it can be used in glaucoma patients.
Indications
- spasm of smooth muscles of internal organs (cardio- and pylorospasm),
- chronic gastroduodenitis,
- gastric and duodenal ulcer,
- biliary stone disease (liver colic),
- chronic cholecystitis,
- postcholecystectomy syndrome,
- hypermotor biliary dyskinesia,
- intestinal colic due to postoperative gas retention,
- colitis,
- proctitis,
- tenesmia,
- meteorrhoea,
- renal stone disease (renal colic),
- pyelitis,
- cerebral, coronary and peripheral artery vasospasm, need to decrease uterine contractions and relieve cervical spasm in labour,
- spasm of smooth muscles during instrumental intervention,
- dysmenorrhea,
- strong labour contractions.
gastric and duodenal colic,
biliary colic./Ulcer of the stomach and duodenum,
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Drotaverine hydrochloride may also be used as an adjuvant in hypertensive crises.
Active ingredient
Drotaverine
Composition
1 tablet contains:
The active ingredient:
drotaverine hydrochloride 40 mg.
Auxiliary substances:
Potato starch 30.71 mg,
Lactose monohydrate 57 mg,
crospovidone (Polyplasdon XL-10) 2.923 mg,
povidone (polyvinylpyrrolidone low molecular weight medical) 5.847 mg,
talc 2.05 mg,
magnesium stearate 1.47 mg.
How to take, the dosage
Orally, with plenty of fluid.
Interaction
When used concomitantly, drotaverine may reduce the antiparkinsonian effect of levodopa.
Special Instructions
Caution should be exercised when using Drotaverin-Teva in patients with arterial hypotension.
Contraindications
- high sensitivity to the active ingredient (drotaverine hydrochloride) or to any of the excipients;
- severe hepatic or renal failure,
- severe heart failure (low cardiac output syndrome,
- AV blockade of degree II and III,
- AV block of degree II and III,
- cardiogenic shock,
- arterial hypotension,
- children younger than 12 years.
cardiogenic shock,
severe heart failure (low cardiac output syndrome),
.
Side effects
Side effects are classified according to the following frequency: very common – at least 10%; common – at least 1%, but less than 10%; infrequent – at least 0.1%, but less than 1%; rare – at least 0.01%, but less than 0.1%; very rare (including individual reports) – less than 0.01%; frequency unknown – not enough data to estimate the frequency of occurrence in the population.
Overdose
There are no data on overdose with Drotaverin-Teva.
Similarities
No-shpa, Drotaverine, Spasmonet, Drotaverine-Teva
Weight | 0.014 kg |
---|---|
Shelf life | 3 years. |
Conditions of storage | Store at a temperature not exceeding 25 ° C. |
Manufacturer | Adipharm EAD, Bulgaria |
Medication form | pills |
Brand | Adipharm EAD |
Other forms…
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