Diuver, tablets 10 mg 20 pcs

Pharmacotherapeutic group: diuretic agent.

AtCode C03CA04

Pharmacological properties

Pharmacodynamics

Indications

– edema syndrome of different genesis, including chronic heart failure, liver, lung and kidney disease;

– arterial hypertension.

Active ingredient

Composition

1 tablet 5 mg contains:

active ingredient: torasemide 5.00 mg;

excipients: lactose monohydrate 58.44 mg, corn starch 14.56 mg, sodium carboxymethyl starch 0.80 mg, colloidal anhydrous silica 0.60 mg, magnesium stearate 0.60 mg.

1 tablet 10 mg contains:

acting substance: torasemide 10.00 mg;

complementary substances: lactose monohydrate 116.88 mg, corn starch 29.12 mg, sodium carboxymethyl starch 1.60 mg, colloidal anhydrous silica 1.20 mg, magnesium stearate 1.20 mg.

How to take, the dosage

Overly, once a day, after breakfast, with a small amount of water.

Oedematous syndrome of different genesis, including. In chronic heart failure, liver, lung and kidney disease

The usual therapeutic dose is 5 mg orally once daily. If necessary, the dose should be gradually increased to 20-40 mg once daily, in some cases up to 200 mg per day. The drug is prescribed for a long period or until the edema disappears.

Arterial hypertension

The initial dose is 2.5 mg (1/2 tablet of 5 mg) once daily. If necessary, the dose may be increased to 5 mg once daily.

Elderly patients do not need dose adjustment.

Interaction

Special Instructions

Synopsis

Contraindications

Side effects

Water-electrolyte and acid-base balance: hyponatremia, hypochloremia, hypokalemia, hypomagnesemia, hypocalcemia, metabolic alkalosis. Symptoms indicative of the development of electrolyte and acid-base state disorders may include headache, confusion, seizures, tetany, muscle weakness, heart rhythm disorders and dyspeptic disorders; hypovolemia and dehydration (more common in elderly patients), which may lead to hemoconcentration with a tendency to develop thrombosis.

Cardiovascular system disorders: excessive decrease in blood pressure, orthostatic hypotension, collapse, tachycardia, arrhythmias, decreased circulating blood volume.

Metabolic side: Hypercholesterolemia, hypertriglyceridemia; transient increase in blood creatinine and urea concentrations; increase in blood uric acid concentration, which may cause or worsen manifestations of gout; decrease in glucose tolerance (possible manifestation of latent diabetes).

Urinary system disorders: oliguria, acute urinary retention (e.g., in prostatic hyperplasia, narrowing of the urethra, hydronephrosis); interstitial nephritis, hematuria, decreased potency.

Gastrointestinal tract disorders: nausea, vomiting, diarrhea, intrahepatic cholestasis, increased activity of “liver” enzymes, acute pancreatitis.

Central nervous system, hearing: disorder of hearing, usually reversible, and/or tinnitus, especially in patients with renal failure or hypoproteinemia (nephrotic syndrome), paresthesias.

Skin side: cutaneous itching, urticaria, other rashes or bullous skin lesions, erythema polymorphicum, exfoliative dermatitis, purpura, fever, vasculitis, eosinophilia, photosensitization; severe anaphylactic or anaphylactoid reactions up to shock, which so far have only been described after intravenous administration.

Peripheral blood: thrombocytopenia; leukopenia; agranulocytosis, aplastic or hemolytic anemia.

Overdose

Pregnancy use

Similarities