Dioxidin, ointment 5% 30 g

A broad spectrum antimicrobial agent. Active against Proteus vulgaris, Pseudomonas aeruginosa, Klebsiella pneumoniae (Friedlander’s bacillus), Escherichia coli, Shigella dysenteria, Shigella flexneri, Shigella boydii, Shigella sonnei, Salmonella spp., Staphylococcus spp., Streptococcus spp., pathogenic anaerobes (Clostridium perfringens). It acts on bacterial strains that are resistant to other antibacterial drugs, including antibiotics. It has no local irritating effect. Development of drug resistance of bacteria is possible. Treatment of burn and purulent-necrotic wounds promotes quicker cleaning of the wound surface, stimulates reparative regeneration and marginal epithelialization and has a positive effect on the course of the wound process.

When applied externally it is partially absorbed from the wound or burn surface. It penetrates well and quickly into all organs and tissues and is excreted by the kidneys. It does not cumulate.

Indications

Wound and burn infection – superficial and deep purulent wounds of different localization (including those with deep purulent cavities – soft tissue abscesses, pelvic cell phlegmons, postoperative wounds of urinary and biliary tracts, purulent mastitis), long-term non-healing wounds and trophic ulcers, soft tissue phlegmons, infected burns, purulent wounds at osteomyelitis, pustular skin diseases.

Composition

Active ingredient:

hydroxymethylquinoxalindioxide5 mg

How to take, the dosage

Outwardly. The ointment is applied in a thin layer directly on the affected area, previously cleared of pus-necrotic masses, or a napkin with it is smeared in a 2-3 mm thick layer; ointment-soaked tampons are inserted into purulent cavities.

The procedure is performed daily or every other day, depending on the condition of the wound and the course of the wound process. The duration of the treatment is up to 3 weeks.

Interaction

Cases of interaction or incompatibility with other drugs have not been described.

Special Instructions

In chronic renal failure the dose is reduced.

Prescribe only if other antimicrobial drugs are ineffective.

Synopsis

The ointment is greenish-yellow in color

Contraindications

Hypersensitivity to the drug components, adrenal insufficiency (including anamnesis), pregnancy, breast-feeding, children under 18 years of age.

Side effects

Local allergic reactions, perineal dermatitis.

Overdose

No cases of overdose have been described.

Pregnancy use

The drug is contraindicated during pregnancy. Administration during breastfeeding is possible only after transfer of the child to artificial feeding.