Dietressa, tablets, 100 pcs.
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Pharmacological properties
Pharmacodynamics
Through allosteric modulation mechanisms the drug sensitizes cannabinoid receptor type I, which is accompanied by increase of its
sensitivity to endogenous cannabinoid neuropeptides. This results in normalization of the endocannabinoid regulation of the mesolimbic system including the food center in the hypothalamus.
It was shown experimentally that when the drug is given to animals the self-stimulation of the lateral hypothalamus is abolished, which indicates saturation of the system of positive emotional reinforcement, reduction of euphoric importance of food, weight gain reduction under high fat diet.
Administration of the drug is accompanied by an inhibitory effect on the processes of obesity: a decrease in food intake and weight loss, without causing both inhibitory and stimulating effects on higher nervous activity.The effect of weight reduction is caused not only by the central, but also by peripheral mechanisms – due to modulation of cannabinoid receptors of adipocytes (fat cells), activation of their basic metabolism.
The drug is not addictive and does not have narcotic effect.
Pharmacokinetics
The sensitivity of modern physico-chemical methods of analysis (gas-liquid chromatography, high performance liquid chromatography,
Chromato-mass spectrometry) does not allow evaluating the content of ultra-low doses of antibodies in biological fluids, organs and tissues, which makes it technically impossible to study the pharmacokinetics of the drug.
Indications
Long-term therapy of patients with overweight or grade I-II obesity (body mass index ≥ 25 kg/m2) in combination with a moderately hypocaloric diet.
Active ingredient
Homeopathic composition
Composition
Active ingredients:
Antibodies to cannabinoid receptor type 1 affinity purified – 0.006 g.*
Excipients: lactose monohydrate, microcrystalline cellulose, magnesium stearate.
* Applied to lactose as a mixture of three active aqueous-alcoholic dilutions of the substance, diluted respectively 10012, 10030, 100200 times.
How to take, the dosage
Oral. It is recommended to take 6 tablets a day, 1-2 tablets (keep in the mouth until dissolved) 15-30 minutes before a meal. It is desirable to combine treatment with a moderately hypocaloric diet.
Take a long time – up to three months.
If necessary, the course can be resumed.
Interaction
Cases of incompatibility with other drugs have not yet been registered.
Special Instructions
The drug contains lactose monohydrate; therefore, it is not recommended for patients with congenital galactosemia, glucose or galactose malabsorption syndrome, or with congenital lactase deficiency.
Dietressa has no effect on the ability to drive vehicles and other potentially dangerous mechanisms.
In a small number of cases at the beginning of therapy with Dietressa a temporary (two to eight days) slight increase of appetite may be observed that does not cause weight gain and does not require discontinuation of the drug.
Synopsis
The tablets are flat and cylindrical, rimmed and beveled, white to off-white in color. The flat side with the rib is labeled MATERIA MEDICA, the other flat side is labeled DIETRESSA
Contraindications
Increased individual sensitivity to the drug components.
Dietressa is not recommended for use in children under 18 years of age due to the lack of data on the effectiveness and safety for this age.
Side effects
When using the drug for the indicated indications and in the indicated dosages side effects have not been revealed. Individual hypersensitivity reactions to the drug components are possible.
Overdose
No cases of overdose have been reported so far. In case of accidental overdose, dyspeptic phenomena due to excipients included in the drug are possible.
Pregnancy use
The safety of using Dietressa in pregnant women and during lactation has not been studied. The risk/benefit ratio should be taken into account if it is necessary to take the drug.
Similarities
Galstena, Gentos, Pumpan, Angin-Hel SD, Bronchalis-Hel, Valerianachel, Vertigohel, Galium-Hel, Gastricumel, Hepar Compositum, Gynecohel, Hormel SN, Discus Compositum, Duodenohel, Climact-Hel, Coenzyme in capsules, Kralonin, Mucosa Compositum, Nervohel, Nux Vomica-Gomaccord, Populus Compositum SR, Renel, Sabal-Gomaccord, Spascuprel, Spigelon, Tartefedrel, Traumel C, Ubichinon Compositum, Helidonium-Gomaccord, Hepel, Cel T, Cerebrum Compositum, Engistol, Eskulus Compositum, Euphorbium compositum Nazentropfen C, Osteohel C, Calcohel, Testis compositum, Ovarium compositum, Tonzilla compositum, Avia-More, Agri, Climaxan, Uspokoy, Edas-131, Edas-306, Edas-801, Dismenorm, Corizalia, Mlecoin, Selencin, Agri children, Acidum-C, Notta, Job-baby, Placenta Compositum, Luffel, Mastodynon, Pulsatilla Compositum, Solidago Compositum, Cutis Compositum, Girel, Momordica Compositum, Rescue Remedy (Bach), Naturkoxinum, Dentokind, Dantinorm Baby, Fleminga ointment, Aflubin, Echinacea Compositum SN, Enterokind, Edas-111, Edas-127, Edas-307M, Mastopol, Homeovox, Remens, Lymphomyositol, Propolis DN, Luffel N, Job-Venum, Copper Horseman, Hemorrhoid Remedy
Weight | 0.050 kg |
---|---|
Shelf life | 3 years. Do not use after the expiration date. |
Conditions of storage | In the dark place at a temperature not exceeding 25 ° C. Keep out of reach of children. |
Manufacturer | Materiala Medica Holding, Russia |
Medication form | pills |
Brand | Materiala Medica Holding |
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