Diclofenac, eye drops 0.1% 5 ml

NSAID, a derivative of phenylacetic acid, has anti-inflammatory and analgesic effects.

Inhibiting COX-1 and COX-2 indiscriminately, it disrupts arachidonic acid metabolism, reduces the number of prostaglandins in the inflammation focus.

When applied topically it reduces swelling and pain in inflammatory processes of non-infectious etiology.

Indications

inhibition of miosis during cataract surgery;
inflammatory processes after surgical interventions;
prevention of cystoid edema of the optic nerve before and after surgery associated with removal and implantation of the lens;
inflammatory processes of a non-infectious nature involving the anterior parts of the eye;
post-traumatic inflammation after penetrating and non-penetrating wounds of the eyeball;
pain syndrome during excimer laser intervention.

Pharmacological effect

NSAIDs, a derivative of phenylacetic acid, have anti-inflammatory and analgesic effects.

By indiscriminately inhibiting COX-1 and COX-2, it disrupts the metabolism of arachidonic acid and reduces the amount of prostaglandins at the site of inflammation.

When applied topically, it reduces swelling and pain in inflammatory processes of non-infectious etiology.

Special instructions

Immediately after instillation, blurred visual perception may occur, which can lead to difficulty driving (including a car) and working at heights. It is necessary to resume such activities only 15 minutes after administration of the drug.

It is not allowed to wear soft contact lenses simultaneously with the administration of the drug. Hard contact lenses should be removed before instillation and reinserted only 20 minutes after administration of the drug.

Active ingredient

Diclofenac

Composition

1 ml contains

Active substance:

diclofenac sodium (diclofenac sodium) – 1 mg

Excipients:

sodium chloride,

propylene glycol,

sodium dihydrogen phosphate dihydrate (sodium phosphate monosubstituted dihydrate),

disodium hydrogen phosphate dodecahydrate (sodium phosphate disubstituted 12-water),

disodium edetate,

sodium hydroxide (1 M solution, up to pH 6.5-7.5),

water d/i.

Contraindications

III trimester of pregnancy;
children’s age (up to 2 years);
hypersensitivity to NSAIDs and other components of the drug.

With caution: “aspirin” asthma, epithelial herpetic keratitis (including a history); diseases that cause blood clotting disorders (including hemophilia). Particular caution should be exercised in patients with gastric and duodenal ulcers in the acute stage, as well as due to the risk of bleeding in patients receiving anticoagulants; during pregnancy, during lactation, pediatric patients (over 2 years old), elderly patients.

Side Effects

Local reactions: burning sensation in the eye, blurred vision (immediately after instillation); clouding of the cornea (cataract), iritis.

Allergic reactions: itching in the eyes, conjunctival hyperemia, angioedema of the face, fever, chills, photosensitivity, skin rash (mostly erythematous), urticaria.

From the digestive system: nausea, vomiting.

Interaction

The interval after using Diclofenac eye drops and other eye drops should be at least 5 minutes. If clinically indicated, it can be combined with eye drops containing glucocorticosteroids.

Overdose

When using Diclofenac eye drops in recommended doses, an overdose is unlikely.

Manufacturer

K.O.Rompharm Company S.R.L., Romania