Diclofenac-Akos, eye drops 0.1% 5 ml

Diclofenac eye drops reduce the synthesis of substances that activate and maintain inflammation (prostaglandins) in the lesion, quickly reducing pain and inflammatory swelling. Diclofenac is superior to ibuprofen, butadione and acetylsalicylic acid (aspirin) in its anti-inflammatory activity.

In the cornea and conjunctiva the active substance reaches maximum concentration 30 minutes after injection of the drug. In the systemic bloodstream Diclofenac is not detected in significant concentrations. It penetrates into the anterior chamber of the eye.

Indications

Diclofenac eye drops are prescribed for the treatment of inflammatory processes of a non-infectious nature (conjunctivitis, keratoconjunctivitis, corneal erosions, inflammation of the conjunctiva and cornea after injury, photophobia after corneal surgery), for the treatment and prevention of post-traumatic inflammation after wounds of the eyeball (penetrating and non-penetrating) as an addition to antibacterial drugs.

The drug is effective for preventing miosis (constriction of the pupil) during cataract surgery, as well as for inflammatory processes after surgery, for the prevention and treatment of cystoid edema of the central part of the retina (macula) after surgical removal of cataracts.

Pharmacological effect

Diclofenac eye drops reduce the synthesis of substances that activate and maintain inflammation (prostaglandins) in the affected area, quickly reducing pain and reducing inflammatory swelling. Diclofenac is superior in its anti-inflammatory activity to ibuprofen, butadione and acetylsalicylic acid (aspirin).

In the cornea and conjunctiva, the active substance reaches its maximum concentration 30 minutes after instillation of the drug. Diclofenac is not detected in the systemic circulation in significant concentrations. Penetrates the anterior chamber of the eye.

Special instructions

It is not recommended to wear contact lenses during treatment with the drug. If it is impossible to refuse their use, you should remove the lenses at least 5 minutes before instilling the drops, and put them on 15 minutes after using the drug.

Diclofenac eye drops affect the ability to engage in activities that require quick reactions and increased attention, so you should not drive vehicles or other potentially dangerous equipment during treatment with the drug.

Active ingredient

Diclofenac

Composition

Eye drops 0.1% in the form of a transparent, colorless or light yellow solution.

1 ml diclofenac sodium 1 mg

Excipients:

sodium chloride,

propylene glycol,

sodium dihydrogen phosphate dihydrate (sodium phosphate monosubstituted dihydrate),

disodium hydrogen phosphate dodecahydrate (sodium phosphate disubstituted 12-water),

disodium edetate,

sodium hydroxide (1 M solution, up to pH 6.5-7.5),

water d/i.

Pregnancy

During pregnancy, the use of the drug is justified if the potential benefit to the mother outweighs the potential risk to the fetus.

Breastfeeding should be stopped while using the drug.

Use in children

Contraindicated in children under 2 years of age.

Contraindications

III trimester of pregnancy;
children’s age (up to 2 years);
hypersensitivity to NSAIDs and other components of the drug.

With caution: “aspirin” asthma, epithelial herpetic keratitis (including a history); diseases that cause blood clotting disorders (including hemophilia). Particular caution should be exercised in patients with gastric and duodenal ulcers in the acute stage, as well as due to the risk of bleeding in patients receiving anticoagulants; during pregnancy, during lactation, pediatric patients (over 2 years old), elderly patients/

Side Effects

Local reactions are possible immediately after instillation: burning, redness of eye tissue, blurred vision, pain, swelling, lacrimation, clouding of the cornea, inflammation of the iris.

Allergic reactions may develop: itching, redness and swelling of the skin and mucous membranes, angioedema of the face, chills, fever, increased sensitivity to light, exudative erythema multiforme, skin rash, nausea, vomiting.

If side effects occur, you should stop taking the drug and consult a doctor.

Interaction

You can use Diclofenac eye drops with antiviral and antibacterial eye drops and ointments, eye corticosteroid medications – in these cases, the break between the use of different drops should be at least 5 minutes.

Overdose

Unlikely to occur if the prescribed dosage is followed.

Storage conditions

In a place protected from light, at a temperature of 15–25 °C (do not freeze)

Shelf life

2 years

Manufacturer

Sintez, Russia