Dibicor, tablets 500 mg 60 pcs
€13.73 €11.44
Dibicor is metabolic.
Pharmacodynamics
Taurine is a natural product of the metabolism of sulfur-containing amino acids: cysteine, cysteamine, methionine. Taurine has osmoregulatory and membrane-protective properties, has a positive effect on the phospholipid composition of cell membranes, and normalizes the exchange of calcium and potassium ions in cells.
Taurine showed properties of inhibitory neurotransmitter, it has anti-stressor effect, can regulate the release of GABA, adrenaline, prolactin and other hormones and regulate responses to them.
Participating in the synthesis of respiratory chain proteins in mitochondria, taurine regulates oxidative processes and exhibits antioxidant properties; it affects enzymes such as cytochromes responsible for the metabolism of various xenobiotics.
Dibicor® improves metabolic processes in the heart, liver and other organs and tissues.
In chronic diffuse liver diseases Dibicor® increases blood flow and reduces the severity of cytolysis. It reduces congestion in the small and large circulatory system: intracardiac diastolic pressure decreases, myocardial contractility increases (maximal contraction and relaxation rate, contractility and relaxation indices).
The drug moderately decreases BP in patients with arterial hypertension and has almost no effect on BP in patients with CVD with lowered BP.
Dibicor® decreases side effects of overdose of cardiac glycosides and slow calcium channel blockers; decreases hepatotoxicity of antifungal agents. Improves performance under heavy physical activity.
Dibicor® decreases blood sugar level in diabetics about 2 weeks after taking the drug. A significant reduction of triglycerides concentration and, to a lesser degree, of cholesterol level and atherogenicity of plasma lipids is also observed. Long-term use of the drug (about 6 months) showed improvement of the microcirculatory blood flow in the eye.
Pharmacokinetics
After a single use of 500 mg of Dibicor® the active substance (taurine) is determined in blood after 15-20 minutes, Cmax is reached after 1.5-2 hours. The drug is completely eliminated in 24 hours.
Indications
Active ingredient
Composition
Tablets
The active ingredient:
taurine 500 mg;
Associates:
MCC 46 mg;
Potato starch 36 mg;
Gelatin 12 mg;
Colloidal silica (Aerosil) 0.6 mg;
Calcium stearate 5.4 mg;
Packed in 30 and 60 pieces.
How to take, the dosage
Orally.
In case of heart failure Dibicor® is taken orally with 250-500 mg (1-2 tablets of 250 mg or 1/2-1 tablets of 500 mg) 2 times a day 20 minutes before meals, treatment course is 30 days. The dose may be increased to 2-3 g/day (8-12 tablets of 250 mg or 4-6 tablets of 500 mg) or reduced to 125 mg (1/2 tablet of 250 mg) per dose.
In intoxication with cardiac glycosides, at least 750 mg/day (3 tablets of 250 mg or 1.5 tablets of 500 mg).
In case of type 1 diabetes mellitus, 500 mg (2 tablets of 250 mg or 1 tablet of 500 mg) 2 times daily in combination with insulin therapy for 3-6 months.
In type 2 diabetes mellitus, 500 mg (2 tablets of 250 mg or 1 tablet of 500 mg) 2 times daily as monotherapy or in combination with other oral hypoglycemic agents.
In case of type 2 diabetes, including with moderate hypercholesterolemia, 500 mg (2 tablets of 250 mg or 1 tablet of 500 mg) 2 times per day, the course length – as recommended by the physician.
As a hepatoprotective agent – 500 mg (2 tablets of 250 mg or 1 tablet of 500 mg) 2 times a day during the course of taking antifungal drugs.
Interaction
Dibicor® can be used with other drugs; it enhances inotropic effect of cardiac glycosides.
Special Instructions
During administration of Dibicor the dose of cardiac glycosides should be reduced sometimes by half, depending on the sensitivity of patients to cardiac glycosides.
The same rule applies to “slow” calcium channel blockers.
Contraindications
Hypersensitivity to the drug; age under 18 years (efficacy and safety not established).
Side effects
Allergic reactions to the ingredients of the drug are possible.
Overdose
There are no data on overdose.
Pregnancy use
There are no data on the use of the drug during pregnancy and lactation.
Similarities
Weight | 0.034 kg |
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Shelf life | 3 years |
Conditions of storage | In a dry, light-protected place at room temperature |
Manufacturer | Pik-Pharma, Russia |
Medication form | pills |
Brand | Pik-Pharma |
Other forms…
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