Diara, 2 mg 12 pcs

Diara is an anti-diarrheal agent.

Loperamide, by binding to opioid receptors of the intestinal wall (modulation of choline and adrenergic neurons through guanine nucleotides), reduces intestinal smooth muscle tone and motility (by inhibiting the release of acetylcholine and prostaglandins).

Delays peristalsis and increases the time of passage of intestinal contents.

It increases tonicity of the anal sphincter and helps retain feces and shortens urges to defecation.

The action comes quickly and lasts for 4-6 hours.

Indications

Active ingredient

Composition

Active ingredient:

loperamide hydrochloride 2.0 mg.

Auxiliary substances:

Polymethylsiloxane,

potato starch,

lactose (milk sugar),

sucrose (sugar) microcrystalline cellulose,

silicon dioxide colloid (aerosil),

aspartame,

povidone (Collidon 90),

xylitol (Xylitab 300),

lactitol, collidone SR,

menthol,

magnesium stearate,

anise oil.

How to take, the dosage

Overly, chewed with water.

Adults in acute and chronic diarrhea are prescribed an initial dose of 2 tablets (4 mg); then 1 tablet (2 mg) after each act of defecation (in case of liquid stools); the maximum daily dose is 8 tablets (16 mg).

Children over 6 years of age in acute diarrhea are prescribed an initial dose of 1 tablet (2 mg), then 1 tablet after each act of defecation (in case of liquid stools); the maximum daily dose is 3 tablets (6 mg).

If stools normalize or if there are no stools for more than 12 hours, treatment with Diara should be stopped.

Special Instructions

If there is no effect within 48 hours, stop using the drug and see a doctor.

Contraindications

With caution: liver failure.

Side effects

Gastralgia, dry mouth, allergic reactions (skin rash), drowsiness, dizziness, intestinal colic, nausea, vomiting, constipation.

Extremely rare – intestinal obstruction.

Overdose

Symptoms: central nervous system (CNS) depression – stupor, impaired coordination of movements, drowsiness, miosis, muscle hypertonia, respiratory depression; intestinal obstruction.

Treatment: the antidote is naloxone; given that the duration of action of loperamide is longer than that of naloxone, it is possible to reintroduce the latter.

Symptomatic treatment: activated charcoal, gastric lavage, artificial lung ventilation (ALV). Medical observation for at least 48 hours is necessary.

Pregnancy use

Diara is not recommended during pregnancy, breastfeeding and children under 6 years of age.

Similarities