Diara, 2 mg 12 pcs

Diara is an anti-diarrheal agent.

Loperamide, by binding to opioid receptors of the intestinal wall (modulation of choline and adrenergic neurons through guanine nucleotides), reduces intestinal smooth muscle tone and motility (by inhibiting the release of acetylcholine and prostaglandins).

Delays peristalsis and increases the time of passage of intestinal contents.

It increases tonicity of the anal sphincter and helps retain feces and shortens urges to defecation.

The action comes quickly and lasts for 4-6 hours.

Indications

Symptomatic treatment of acute and chronic diarrhea of ​​various origins (allergic, emotional, medicinal, radiation);
when changing the diet and quality of food, when metabolism and absorption are impaired;
as an adjuvant for diarrhea of ​​infectious origin;
regulation of stool in patients with ileostomy.

Pharmacological effect

Diara is an antidiarrheal agent.

Loperamide, by binding to opioid receptors of the intestinal wall (modulation of choline and adrenergic neurons through guanine nucleotides), reduces the tone and motility of intestinal smooth muscles (by inhibiting the release of acetylcholine and prostaglandins).

Slows down peristalsis and increases the transit time of intestinal contents.

Increases the tone of the anal sphincter, promotes fecal retention and reduces the urge to defecate.

The action comes quickly and lasts 4-6 hours.

Special instructions

If there is no effect within 48 hours, you should stop using the drug and consult a doctor.

Active ingredient

Loperamide

Composition

Active ingredient:

loperamide hydrochloride 2.0 mg.

Excipients:

polymethylsiloxane,

potato starch,

lactose (milk sugar),

sucrose (sugar) microcrystalline cellulose,

colloidal silicon dioxide (aerosil),

aspartame,

povidone (Kollidon 90),

xylitol (Xylitab 300),

lactitol, Kollidon SR,

menthol,

magnesium stearate,

anise oil

Pregnancy

Diara is not recommended for use during pregnancy, breastfeeding and children under 6 years of age.

Contraindications

Hypersensitivity to the drug;
diverticulosis;
intestinal obstruction;
ulcerative colitis in the acute stage;
diarrhea due to acute pseudomembranous enterocolitis;
as monotherapy for dysentery and other infections of the gastrointestinal tract (GIT);
pregnancy (first trimester) and lactation period;
children under 6 years old.

With caution: liver failure.

Side Effects

Gastralgia, dry mouth, allergic reactions (skin rash), drowsiness, dizziness, intestinal colic, nausea, vomiting, constipation.

Extremely rare – intestinal obstruction.

Overdose

Symptoms: depression of the central nervous system (CNS) – stupor, impaired coordination of movements, drowsiness, miosis, muscle hypertension, respiratory depression; intestinal obstruction.

Treatment: antidote – naloxone; Given that the duration of action of loperamide is longer than that of naloxone, repeated administration of the latter is possible.

Symptomatic treatment: activated charcoal, gastric lavage, artificial pulmonary ventilation (ALV). Medical supervision is required for at least 48 hours.

Storage conditions

Store in a dry place, protected from light, at a temperature not exceeding 25°C.

Shelf life

2 years.

Manufacturer

Alium JSC, Russia