Dexpanthenol-Vertex, 5% ointment 30 g

Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid is a water-soluble B vitamin and is a part of coenzyme A. It stimulates skin regeneration, normalizes cell metabolism and increases the strength of collagen fibers.

The increased need for pantothenic acid is observed when there is damage to the skin or tissues, and its deficiency can be compensated by topical application of dexpanthenol.

Optimal molecular weight, hydrophilicity and low polarity allow its penetration into all skin layers. It has a regenerating, mild anti-inflammatory effect.

Pharmacokinetics

When applied topically, it is rapidly absorbed and converted to pantothenic acid and binds to plasma proteins (mainly beta-globulin and albumin).

Indications

Violations of the integrity of the skin caused by mechanical, chemical, temperature factors or after surgical interventions:

burns of various origins (including sunburn);
scratches, abrasions, wounds; bedsores; poorly healing skin grafts;
aseptic postoperative wounds;

Inflammatory processes on the skin; dermatitis; boils; trophic ulcers of the lower extremities; skin care around tracheostomy, gastrostomy and colostomy.

Treatment and prevention of the consequences of adverse effects on the skin of environmental factors (cold, wind, dampness).

In children – diaper dermatitis, scratches and minor irritation after exposure to the sun, ultraviolet and x-rays; treatment and prevention of diaper rash.

Cracks and inflammation of the nipples of the breast in nursing mothers.

It is also used to treat and protect dry skin as a source of neutral fats and dexpanthenol.

Pharmacological effect

Dexpanthenol is a derivative of pantothenic acid. Pantothenic acid, a water-soluble B vitamin, is a component of coenzyme A. It stimulates skin regeneration, normalizes cellular metabolism, and increases the strength of collagen fibers.

An increased need for pantothenic acid is observed when the skin or tissues are damaged, and its deficiency can be compensated for by the local use of dexpanthenol.

Optimal molecular weight, hydrophilicity and low polarity make it possible to penetrate into all layers of the skin. Has a regenerating, weak anti-inflammatory effect.

Pharmacokinetics

When applied topically, it is quickly absorbed and converted into pantothenic acid and binds to plasma proteins (mainly beta-globulin and albumin).

Special instructions

Treatment of trophic ulcers and poorly healing skin grafts should be carried out under the supervision of the attending physician.

Do not apply to wet wounds.

Active ingredient

Dexpanthenol

Composition

100 g ointment for external use contains

Active ingredient:

dexpanthenol – 5.0 g.

excipients:

lanolin anhydrous,

cholesterol,

Vaseline,

Vaseline oil,

isopropyl myristate,

methyl parahydroxybenzoate (nipagin),

propyl parahydroxybenzoate (nipazole),

purified water.

Pregnancy

Caution according to indications: cracks and inflammation of the nipples of the breast in nursing mothers.

Contraindications

Hypersensitivity to any of the components of Dexpanthenol.

Side Effects

Side effects develop extremely rarely.

Slightly expressed allergic reactions are possible.

Storage conditions

In a dry place, protected from light, at a temperature not exceeding 25 °C

Shelf life

2 years

Manufacturer

Vertex, Russia