Delagil, tablets 250 mg, 30 pcs.

An antiprotozoal agent, it also has immunosuppressive and anti-inflammatory effects.

Delagil causes death of asexual erythrocytic forms of all types of plasmodia.

It has gametocidal action, except for Plasmodium falciparum (shows antigametocidal action).

Indications

— malaria (prevention and treatment of all types);
– extraintestinal amebiasis;
– amoebic liver abscess;
— systemic lupus erythematosus (chronic and subacute forms);
— rheumatoid arthritis;
— scleroderma;
– photodermatosis.

Pharmacological effect

An antiprotozoal agent, it also has an immunosuppressive and anti-inflammatory effect.

Delagil causes the death of asexual erythrocyte forms of all types of plasmodium.

Has a gametocidal effect, with the exception of Plasmodium falciparum (exhibits an antigametocidal effect).

Active ingredient

Chloroquine

Composition

1 tablet contains chloroquine 250 mg

Contraindications

— malaria (prevention and treatment of all types);
– extraintestinal amebiasis;
– amoebic liver abscess;
— systemic lupus erythematosus (chronic and subacute forms);
— rheumatoid arthritis;
— scleroderma;
– photodermatosis.

Side Effects

– From the nervous system: dizziness, psychomotor agitation, headache, insomnia, psychosis, neuropathies, seizures.

– From the musculoskeletal system: myopathies.

– On the part of sensitive analyzers: hearing loss, tinnitus, weakened visual perception, corneal clouding, retinopathy, accommodation disturbance, reversible keratopathy.

– From the digestive system: nausea, vomiting, diarrhea, anorexia, spastic abdominal pain, weight loss, hepatotoxicity.

– From the vascular system: possible development of arterial hypotension, cardiomyopathy.

– Skin manifestations: dermatitis, itching, rash, photosensitivity, skin pigmentation disorder, hair loss.

Interaction

The combined use of other antimalarial drugs enhances the effect of Delagil.

Cannot be taken together with gold preparations, cytostatics, penicillamine, levamisole, because this may increase the side effects of the drug.

When taken together with MAO inhibitors, the toxic effect increases.

With long-term use of Delagil together with cardiac glycosides, the development of glycoside intoxication is possible.

Ethanol enhances the toxic effect of Delagil on the liver.

Overdose

In case of an overdose of this drug, loss of consciousness, vomiting, respiratory depression, convulsions, and collapse are observed.

In case of overdose, it is necessary to rinse the stomach and take adsorbents orally.

In severe cases of poisoning, plasmapheresis and peritoneal dialysis may be used.

Storage conditions

At a temperature not exceeding 25 °C

Shelf life

5 years

Manufacturer

Switzerland