Coldrex HotRem, lemon 5 g 5 pcs

Paracetamol is an analgesic and antipyretic. The mechanism of its action is presumably to inhibit the synthesis of prostaglandins, mainly in the central nervous system.

Paracetamol has an extremely small effect on the synthesis of prostaglandins in the peripheral tissues, it does not change the water-electrolyte exchange and does not damage the mucous membrane of the gastrointestinal tract.

Indications

Active ingredient

Composition

Composition per sachet 5 g:

Active ingredients:

paracetamol 750 mg,

phenylephrine hydrochloride 10 mg

ascorbic acid 60 mg.

Auxiliary substances: citric acid 600.0 mg, sodium saccharinate 10.0 mg, sodium citrate 500.0 mg, lemon flavoring PHS-163671 100.0 mg, honey flavoring PFW PHS-050860 75.0 mg, honey flavoring Felton F7624P 125.0 mg, caramel dye 626 50.0 mg, corn starch 200.0 mg, aspartame 50.0 mg, sucrose 2468.50 mg.

How to take, the dosage

Interaction

Special Instructions

Synopsis

Contraindications

Side effects

Side effects are classified by organ system and frequency. The frequency of side effects is defined as follows: very common (greater than or equal to 1/10) common (greater than or equal to 1/100 and less than 1/10) infrequent (greater than or equal to 1/1000 and less than 1/100) rare (greater than or equal to 1/10 000 and less than 1/1000) and very rare (greater than or equal to 1/100 000 and less than 1/10 000).

The drug is usually well tolerated at the recommended doses.

Paracetamol rarely has side effects.

Hematopoietic organs: Very rare: thrombocytopenia leukopenia agranulocytosis.

Allergic reactions: Very rare: anaphylactic shock. hypersensitivity reactions including skin rash urticaria angioedema Stevens-Johnson syndrome.

Respiratory system disorders: Very rare: bronchospasm in patients sensitive to acetylsalicylic acid and other non-steroidal anti-inflammatory drugs (NSAIDs).

Hepatic and biliary tract disorders: Very rare: liver dysfunction. When prolonged use with exceeding the recommended dose, hepatotoxic and nephrotoxic effects may be observed.

Phenylephrine

Nervous system disorders: Often: headache. dizziness insomnia.

Central nervous system disorders: Often: increased excitability. Very rare: irritability nervous tension.

Cardiovascular system: Often: increased blood pressure. Rarely: tachycardia palpitations.

Digestive system disorders: Often: nausea vomiting.

Senses: Rarely: mydriasis acute glaucoma attack in most cases in patients with closed-angle glaucoma.

Skin and subcutaneous tissue disorders: Rare: allergic reactions (skin rash urticaria allergic dermatitis).

Perior urinary system disorders: Rarely: dysuria delayed urination in patients with bladder outlet obstruction with prostatic hypertrophy.

Ascorbic acid

The incidence of side effects has not been established.

Allergic reactions: skin rash skin hyperemia.

Digestive system disorders: irritation of the mucous membranes of the gastrointestinal tract.

Hematopoietic organs: thrombocytosis hyperprothrombinemia erythropenia neutrophilic leukocytosis hypokalemia.

Moderate pollyacuria may occur when taking ascorbic acid more than 600 mg/day.

If side effects occur, stop taking the drug immediately and see a physician as soon as possible.

If any of the side effects listed in the instructions worsen, or if you notice any other side effects not listed in the instructions, tell your doctor.

Stop taking the medicine and see your doctor immediately if:

You have allergic reactions: itching or redness of the skin difficulty breathing or swelling of the lips of the tongue of the throat or face;

– a rash or peeling on the skin forming ulcers on the mucosa of the mouth;

– you experience bruising or bleeding;

– you experience loss of vision. This may be due to elevated intraocular pressure. Very rarely, but most likely, this side effect occurs in patients with glaucoma;

You have a palpitations or feel an increase in heart rate or a disturbance in heart rhythm;

You have difficulty urinating. This side effect is more common in patients with prostatic hypertrophy.

Do not take the drug if you have previously had breathing problems while taking acetylsalicylic acid or non-steroidal anti-inflammatory drugs.

Overdose

Pregnancy use

Similarities