Chronotron 20 mg/ml 2 ml, syringe

Joint diseases accompanied by pain syndrome, caused by degenerative or post-traumatic conditions or changes in the joints. This product, thanks to its visco-elastic and lubricating properties, allows the restoration of optimal rheological and physiological conditions for the functioning of the joints. By improving the characteristics of synovial fluid, the product protects the joints. These properties help to improve joint function and reduce joint pain.

Active ingredient

Composition

How to take, the dosage

The product should be administered as intra-articular injections, using a sterile 20G needle. Intra-articular injection must be performed by a qualified physician, in accordance with the technical requirements and aseptic rules to be observed for this mode of administration. Given the viscosity of the solution, the needle should be tightly threaded onto the luer tip of the syringe barrel in order to ensure tightness and prevent leakage of the solution between the needle and syringe during product application.

Dosage
In general, unless otherwise advised by the physician: Make one intra-articular injection with 2.0 ml of the product (40 mg polynucleotide), once a week for 3-6 weeks.

Special Instructions

Precautions for use
The product is intended for single use.
The product should be used with extreme caution in case of congestion in the lymphatic or venous system of the lower extremity whose joints are being treated. It is recommended to eliminate any signs of joint swelling (if any), before starting the administration of the product. Patients receiving intra-articular injections should avoid vigorous physical activity that could damage the joint, and resume standard activity after several days.
The product should not be used simultaneously with disinfectants containing quaternary ammonium salts or chlorhexidine.
The product should not be injected intravascularly, periarticularly, into the synovial membrane, or into the joint capsule.
The product should not be injected if there is contamination in the syringe.

Special Notes
Intra-articular injections should only be performed by medical professionals.
Before using the syringe, make sure that the packaging is completely sealed: do not use if the sterile packaging is damaged or has already been opened. Do not use the product after the expiration date printed on the package. The expiration date refers to the unopened product if stored correctly. The product should be used immediately after opening and disposed of after use.
The product should only be distributed as prescribed by a physician.

Synopsis

Contraindications

Side effects

During the use of CHRONOTRON, some unwanted effects associated with the clinical practice of intra-articular injections may occur, including localized pain, fever, redness and swelling.

These symptoms can be treated by resting the joint and applying ice to the joint, and these symptoms are usually resolved within a short period of time. If symptoms persist, a physician should be consulted. Physicians should advise patients to report any adverse events that may develop after treatment.