Cavinton Forte, tablets 10 mg 90 pcs

Cavinton forte is a drug that improves cerebral circulation. It improves the metabolism of the brain, increasing the consumption of glucose and oxygen by the brain tissue.

Enhances resistance of neurons to hypoxia by increasing glucose transport to the brain through the BBB; switches the process of glucose breakdown to a more energy-saving aerobic route; selectively blocks Ca2+-dependent phosphodiesterase; increases AMP and cGMP levels in the brain.

Enhances ATP concentration and ATP/AMP ratio in brain tissues; increases brain noradrenaline and serotonin metabolism; stimulates the ascending branch of the noradrenergic system, has antioxidant effect.

Reduces platelet aggregation and increased blood viscosity; increases the deformation ability of red blood cells and blocks red blood cell utilization of adenosine; promotes oxygenation of red blood cells. It enhances the neuroprotective effect of adenosine.

It increases cerebral blood flow; it reduces resistance of cerebral blood vessels without significant changes in the indices of systemic circulation (BP, minute volume, HR, RPS). Not only it does not have the effect of “stealing” but also increases blood supply primarily in the ischemic areas of the brain with low perfusion.

Indications

In neurology – acute and chronic cerebral circulatory failure (transient ischemia, progressive stroke, post-stroke conditions, vascular dementia, cerebral atherosclerosis, post-traumatic and hypertensive encephalopathy, vertebrobasilar insufficiency); mental and neurological disorders in patients with cerebrovascular insufficiency (including memory impairment, dizziness, headache, aphasia, apraxia, movement disorders).

In ophthalmology – vascular diseases of the eyes (atherosclerosis, vasospasm of the choroid and retina, degenerative diseases of the choroid, retina or macula, arterial and venous thrombosis or embolism, secondary glaucoma).

In ENT practice – hearing loss (vascular, toxic or age-related), Meniere’s disease, cochleovestibular neuritis, tinnitus, dizziness (of labyrinthine origin); vasovegetative manifestations of menopausal syndrome.

Pharmacological effect

Cavinton forte is a drug that improves cerebral circulation. Improves brain metabolism by increasing the consumption of glucose and oxygen by brain tissue.

Increases the resistance of neurons to hypoxia, enhancing the transport of glucose to the brain through the BBB; transfers the process of glucose breakdown to the more energy-efficient aerobic pathway; selectively blocks Ca2+-dependent phosphodiesterase; increases levels of AMP and cGMP in the brain.

Increases the concentration of ATP and the ATP/AMP ratio in brain tissue; enhances the exchange of norepinephrine and serotonin in the brain; stimulates the ascending branch of the noradrenergic system and has an antioxidant effect.

Reduces platelet aggregation and increased blood viscosity; increases the deforming ability of red blood cells and blocks the utilization of adenosine by red blood cells; helps increase oxygen delivery by red blood cells. Strengthens the neuroprotective effect of adenosine.

Increases cerebral blood flow; reduces the resistance of cerebral vessels without significant changes in systemic circulation parameters (BP, minute volume, heart rate, peripheral vascular resistance). Not only does it not have a “stealing” effect, but it also increases blood supply, primarily in ischemic areas of the brain with low perfusion.

Special instructions

Cavinton does not have hepato- and nephrotoxic effects, therefore, when prescribing the drug to patients with liver and kidney diseases, no dosage adjustment is required.

In case of lactose intolerance, please note that each tablet contains 83 mg of lactose.

Use in pediatrics

It is not recommended to prescribe the drug to children under 18 years of age due to the lack of experience in using Cavinton in this category of patients.

Active ingredient

Vinpocetine

Composition

1 tablet contains vinpocetine 10 mg;

excipients:

colloidal silica anhydrous,

magnesium stearate,

talc,

starch,

lactose

Contraindications

Pregnancy; lactation; severe forms of heart failure and cardiac arrhythmias; hypersensitivity to vinpocetine or other components of the drug.

Side Effects

From the cardiovascular system: it is possible to increase the manifestations of existing arrhythmia.

From the digestive system: nausea, heartburn, dry mouth.

From the central nervous system: headache, dizziness, sleep disturbance, weakness.

Allergic reactions: skin rash, urticaria.

Skin reactions: hyperemia of the skin.

Storage conditions

In a place protected from light, at a temperature of 15–30 °C

Shelf life

5 years

Manufacturer

Gedeon Richter-RUS, Russia