Castor oil for oral administration 30 g

• acute constipation;
• refusals;
• food intoxications;
• colonial cleansing before diagnostic procedures;
• purge of bowel before diagnostic procedures.
• weakness of labor (as part of complex therapy)
• burning, wounds, skin ulcers, hyperkeratosis
• to stimulate hair growth.

.

Active ingredient

Common castor oil seeds

Composition

active ingredient:

castor oil

How to take, the dosage

As a laxative administered to adults 15 – 30 g once a day. When cleansing bowels before diagnostic procedures it is taken 2 – 6 hours before the study. Children at the age of 12-14 years old are prescribed 5 – 15 g once a day.

In case of weakness of labor strength and in order to stimulate labor activity the castor oil is administered in dose of 40-50 g once against the background of using medicines stimulating uterine contractility.

In dermatological practice to soften the skin and remove scales from excessive keratinization it is used topically in the form of boltushka in ethyl alcohol in 1:10 ratio with 2% salicylic acid added (10 g of castor oil, 2 g of salicylic acid, ethyl alcohol up to 100 ml). Boltushka shall be rubbed into the lesion once a day for 4 – 7 days, after which mechanical cleaning of the lesion shall be carried out and treatment shall be continued.

In the treatment of burns, skin wounds it is prescribed topically in the form of boltushkas and emulsions in distilled water 1 – 2 times a day under a bandage.

For strengthening hair growth a solution of 10 g castor oil and 100 ml of 96% ethyl alcohol is prepared and rubbed into the scalp.

Interaction

In concomitant use reduces absorption of fat-soluble vitamins A, D and K. In doses up to 4 g / day increases absorption of fat-soluble drugs – male fern extract, mebendazole, griseofulvin, probucol.

In concomitant use with saline laxatives a sharp increase in the laxative effect is possible.

M-cholinoblocking agents (atropine sulfate, platifiline, pirenzepine), antispasmodics (papaverine, drotaverine) weaken the effect of castor oil.

The anticholinesterase agents (neostigmine, pyridostigmine, rivastigmine) and glycerol increase the laxative effect of castor oil.

It enhances the effect of agents that stimulate myometrial contractile activity (methylergometrine, ergometrine, oxytocin, prostaglandins) up to the threat of uterine rupture in labor.

When used topically, it increases the transcutaneous absorption of drugs applied together with it on the skin.

Special Instructions

Impact on driving and operating machinery. During administration of castor oil it is not recommended to drive a motor vehicle, you should refrain from other operator’s activities due to possible impairment of concentration during the onset of the effect.

Caution when using. Castor oil should not be used as a laxative for more than 3 days because it may interfere with digestion and absorption of vitamins A and D, and cause hypovitaminosis. Castor oil should not be used with medicinal products derived from the male fern because this could lead to systemic absorption and neurotoxic effects.

Contraindications

• individual intolerance;
• chronic constipation;
• acute inflammatory bowel disease (including appendicitis);
• mechanical intestinal obstruction;
• abdominal pain of unclear genesis;
• intestinal and uterine bleeding;
acute and chronic glomerulonephritis;
• tubulointerstitial nephritis;
• poisoning with fat-soluble poisons (including gasoline, carbon tetrachloride, male fern extract);
• pregnancy;
• lactation period;
• childhood (under 12 years).

.

Side effects

• abdominal pain, nausea;
• digestive disorders, enterocolitis with repeated use;
• hypovitaminosis A and D with repeated use.Hypovitaminosis A and D with repeated use;
• blood rush to the pelvic organs;
• addiction with repeated use.

.

Overdose

It develops when ingestion of castor oil in a dose greater than 7 g/kg body weight. Diarrhea, abdominal cramps, impaired renal function, dizziness, hallucinations, loss of consciousness are characteristic.

The specific antidotes are atropine sulfate and loperamide. Measures of care include withdrawal of the drug, replenishment of fluid and electrolyte losses (combined oral and intravenous administration is preferred), supportive and symptomatic therapy aimed at elimination of the resulting disorders. If neurotoxic effects develop, diazepam 5 – 10 mg intravenously is administered.