Cardiomagnil, 75 mg+15, 2 mg 30 pcs

The drug Cardiomagnil has antiplatelet action, it is a non-steroidal anti-inflammatory agent. The anti-inflammatory effect is associated with irreversible inhibition of cyclooxygenase-1 through acetylation reaction. Thromboxane A2 under the influence of acetylsalicylic acid (ASA) is reduced by selective inhibition of its synthesis. It is likely that there are other mechanisms to reduce platelet aggregation during the action of ASA.

Indications

Used for the prevention of thrombosis in cardiovascular surgery (in the postoperative period after coronary angioplasty, coronary artery bypass grafting).

Pharmacological effect

The drug Cardiomagnyl has an antiplatelet effect and is a non-steroidal anti-inflammatory drug. The anti-inflammatory effect is associated with irreversible inhibition of cyclooxygenase-1 due to the acetylation reaction. Thromboxane A2 under the influence of acetylsalicylic acid (ASA) is reduced as a result of selective inhibition of its synthesis. There are probably other mechanisms for reducing platelet aggregation under the influence of ASA.

Special instructions

Prescribe with caution for gout and hyperuricemia (reduces the excretion of uric acid).

Active ingredient

Acetylsalicylic acid, [Magnesium hydroxide]

Composition

Active components:

Contraindications

• Kidney failure;
• taking methotrexate at a dose of more than 15 mg/week;
• age up to 18 years.
– a tendency to bleeding or a recent episode of bleeding (hemorrhagic diathesis, hemorrhagic stroke, hypothrombinemia, gastrointestinal bleeding, hemophilia);
• bronchial asthma in response to the administration of ASA;
• allergy to the components of the drug (especially ASA);
• deficiency of glucose-6-phosphate dehydrogenase;

Side Effects

Hemorrhagic stroke, bleeding from the gastrointestinal tract, allergic reactions, bronchospasm.

Interaction

Antacids and cholestyramine reduce the absorption of the drug.

Overdose

If signs of overdose are detected, the patient is hospitalized, the stomach is washed, sorption enteral drugs are prescribed, and, if necessary, alkaline diuresis is provided.

Storage conditions

The storage location must be protected from children, light and moisture.

Shelf life

Shelf life – 5 years at temperatures not exceeding 25°C

Manufacturer

Takeda Pharmaceuticals LLC, Russia