Candide, vaginal tablets 500 mg

Candid – broad spectrum antifungal.

Pharmacodynamics

The antimycotic effect of the active active ingredient – clotrimazole (imidazole derivative) is associated with disruption of ergosterol synthesis, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.

In low concentrations it is fungistatic and in high concentrations it is fungicidal, and not only on proliferating cells. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in hydrogen peroxide concentration to toxic levels, which also contributes to the destruction of fungal cells.

It is effective against dermatophytes, yeast-like and mold fungi as well as against the causative agent of variegated lichen (Pityriasis versicolor) and erythrazma causative agent. It has antimicrobial action against Gram-positive (staphylococci, streptococci) and Gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

Indications

Active ingredient

Composition

Vaginal tablets

1 tablet contains:

The active ingredient:

Clotrimazole 500 mg

Associates:

Lactose

Starch

Sodium carboxymethyl starch

Purified talc

Magnesium stearate

Colloidal silicon dioxide

Methyl parahydroxybenzoate (methyl paraben)

Propyl parahydroxybenzoate (propyl paraben)

How to take, the dosage

Intravenously.Injected intravaginally, deeply, in a “supine” position with the legs slightly bent.

500 mg once in the evening.

The second course of treatment is possible after the doctor’s consultation.

For sanation of the birth canal a single administration of 1 tablet is recommended.

Contraindications

With caution: period of breastfeeding.

Overdose

The use of the drug in high doses does not cause any reactions and life-threatening conditions.

Symptoms (in case of unintended use of the drug orally): anorexia, nausea, vomiting, gastralgia, liver dysfunction; rarely – somnolence, hallucinations, pollakiuria, skin allergic reactions.

Treatment:prescription of activated charcoal, if necessary – symptomatic therapy; there is no specific antidote.

Similarities