Candide, vaginal tablets 500 mg

Candid – broad spectrum antifungal.

Pharmacodynamics

The antimycotic effect of the active active ingredient – clotrimazole (imidazole derivative) is associated with disruption of ergosterol synthesis, which is part of the cell membrane of fungi, which changes the membrane permeability and causes subsequent cell lysis.

In low concentrations it is fungistatic and in high concentrations it is fungicidal, and not only on proliferating cells. In fungicidal concentrations, it interacts with mitochondrial and peroxidase enzymes, resulting in an increase in hydrogen peroxide concentration to toxic levels, which also contributes to the destruction of fungal cells.

It is effective against dermatophytes, yeast-like and mold fungi as well as against the causative agent of variegated lichen (Pityriasis versicolor) and erythrazma causative agent. It has antimicrobial action against Gram-positive (staphylococci, streptococci) and Gram-negative bacteria (Bacteroides, Gardnerella vaginalis), as well as against Trichomonas vaginalis.

Indications

Mucocele (candidiasis), Itching and dryness in the genital area, Inflammation of the female genitalia

• genital infections caused by yeast-like fungi of the genus Candida and/or Trichomonas vaginalis. (Candida vulvovaginitis, trichomoniasis);

• Genital superinfections caused by clotrimazole-sensitive microorganisms;

• sanation of the birth canal before delivery.

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Active ingredient

Clotrimazole

Composition

Vaginal tablets

1 tablet contains:

The active ingredient:

Clotrimazole 500 mg

Associates:

Lactose

Starch

Sodium carboxymethyl starch

Purified talc

Magnesium stearate

Colloidal silicon dioxide

Methyl parahydroxybenzoate (methyl paraben)

Propyl parahydroxybenzoate (propyl paraben)