Candide B, cream 15 g

Candid-B – antifungal topical, anti-inflammatory topical, anti-exudative, antipruritic, anti-allergic.

Pharmacodynamics

Clotrimazole – imidazole derivative, antifungal agent of broad spectrum action.

The effect of the drug is associated with disruption of the synthesis of ergosterol, which is part of the cell membrane of fungi, which causes changes in its structure and properties and leads to cell lysis. Dermatophytes, yeasts (genus Candida, Torulopsis glabrata, Rhodotorula), molds, as well as Pityriasis versicolor (herpes simplex) and erythrazma are sensitive to clotrimazole.

In addition, it has antimicrobial action against Gram-positive (staphylococci and streptococci) and Gram-negative bacteria (Bacteroides, Gardnerella vaginalis) and against Trichomonas vaginalis.

Beclomethasone dipropionate has anti-inflammatory, anti-allergic, anti-exudative and antipruritic effects.

When used topically, beclomethasone dipropionate suppresses inflammatory and allergic skin reactions as well as those associated with increased proliferation, resulting in a reduction of objective symptoms (erythema, edema, lichenification) and subjective sensations (itching, irritation, pain).

Indications

Fungal skin infections caused by susceptible microorganisms (including dermatomycosis, epidermophytosis, dermatosis complicated by secondary infection), especially against the background of eczematous lesions.

Active ingredient

Composition

1 g cream contains:

Active ingredients:

Clotrimazole 10 mg

Beclomethasone 250 mcg

Associates:

White Vaseline jelly

Liquid paraffin

Cetomoacrogol wax

/p>

Benzyl alcohol

Methylparaben

Propylparaben

/p>

Butylated hydroxytoluene

Propylene glycol

Single-substituted sodium phosphate

Anhydrous sodium phosphate

Purified water.

How to take, the dosage

Externally, on previously washed and dried affected areas of the skin, rubbing lightly, apply a thin layer 2-3 times a day.

– in inguinal epidermophytosis,smooth skin microsporia and candidiasis.

-treatment course – 2 weeks;

– epidermophytosis of the feet – 4 weeks.

If long-term use is necessary, use less often, every other day.

In the therapy of chronic diseases, treatment should be continued for some time after all symptoms have disappeared to avoid a recurrence of the disease.

Special Instructions

If a hypersensitivity reaction (itching, burning or redness) develops on the skin during the first use of Candide B Cream, immediately discontinue use and consult a physician.

Long-term treatment should be avoided if possible, especially in children, because of possible suppression of adrenal function.

Application over a large surface area or use of occlusive dressings may lead to systemic absorption of beclomethasone.

Contact of the drug to the eyes should be avoided; do not apply to the skin in the eye area or to the mucous membranes.

The development or spread of infection requires withdrawal of the drug and prescription of antimicrobial therapy.

Bacterial infection is maintained in warm moist conditions, including occlusive dressings, so the skin should be cleaned before applying the cream.

There is no evidence of adverse effects of Candide B Cream on driving and operating ability.

Contraindications

Hypersensitivity, skin tuberculosis, chickenpox, measles, herpes, vaccination, syphilitic skin rashes.

With caution. Hypersensitivity, skin tuberculosis, chickenpox, herpes, vaccination, syphilitic skin rashes.

Side effects

The side effects are usually mild.

Possible local allergic reactions are redness of the skin, burning and tingling sensations at the site of application.

In rare cases, as with other GKS, acne-like changes, hypopigmentation, stretch marks, skin atrophy, hypertrichosis, telangiectasia, and secondary skin infections may develop.

Overdose

Symptoms:

Long-term use of beclomethasone on large skin surfaces with compromised integrity or with the use of an occlusive dressing, as well as long-term use in children, may result in adverse effects associated with suppression and insufficiency of adrenal cortical function.

Treatment:

Cancellation of the drug and, if necessary, symptomatic therapy.

Pregnancy use

The external use of Candida B cream in pregnant women is permitted when the anticipated benefit to the mother outweighs the risk to the fetus.

In such cases, the use of the drug should be of short duration and limited to small areas of the skin.

It is not known whether the drug passes into the mother’s milk, so during breast-feeding the use of Candida B is only permitted under strict indications, and the drug must not be applied to the mammary gland skin before breast-feeding.