Calcium gluconate, tablets 500 mg 30 pcs

Calcium ions drug, replenishes the lack of calcium ions required for the transmission of nerve impulses, reduction of skeletal and smooth muscles, myocardial activity, formation of bone tissue, blood clotting.

Pharmacokinetics

Approximately 1/5-1/3 of ingested calcium gluconate is absorbed in small intestine; this process depends on the presence of vitamin D, pH, specifics of diet and the presence of factors that can bind calcium ions. Absorption of calcium ions increases with calcium deficiency and a diet with reduced calcium ions. About 20% is excreted by the kidneys, the rest (80%) by the intestine (actively excreted by the terminal wall of the gastrointestinal tract).

Indications

Parathyroid gland hypofunction (latent tetany, osteoporosis), disorders of vitamin D metabolism: rickets (spasmophilia, osteomalacia), hyperphosphatemia in patients with chronic renal failure.
Conditions accompanied by increased calcium requirement (during pregnancy, unbalanced and inadequate diet).

Chronic intoxication with magnesium salts, oxalic and hydrofluoric acids and their soluble salts (upon interaction with calcium gluconate insoluble salts and non-toxic calcium oxalate and calcium fluoride are formed).

Hyperkalemic form of paroxysmal myoplegia.

Active ingredient

Calcium gluconate

Composition

One tablet:
active ingredient:
calcium gluconate monohydrate – 0,5 g
excipients:
potato starch – 0,0194 g
talc – 0,0053 g
calcium stearate – 0,0053 g.

How to take, the dosage

Inside, before a meal or 1-1.5 hours after a meal (with milk), adults – 1-3 g (2-6 pills), 2-3 times a day. Children 5 to 6 years – 2-3 tablets (1-1.5 g), 7 to 9 years – 3 to 4 tablets (1.5-2 g), 10 to 14 years – 4-6 tablets (2-3 g). Take 2-3 times a day.

Interaction

Simultaneous use with quinidine may slow intraventricular conduction and increase quinidine toxicity.

Delays absorption of tetracyclines, digoxin, oral iron drugs (interval between their doses should be at least 2 hours). In combination with thiazide diuretics it can increase hypercalcemia, decreases the effect of calcitonin in hypercalcemia, decreases bioavailability of phenytoin.

Special Instructions

Calcium preparations should be prescribed with caution in patients with heart disease or sarcoidosis. Careful monitoring of blood calcium levels and urinary calcium excretion is necessary when high doses are prescribed, especially in children.

The treatment should be stopped if blood calcium levels exceed 2.625 – 2.75 mmol/l or if urinary calcium excretion exceeds 5 mg/kg. High vitamin D intake should be avoided during calcium therapy.

Patients with mild hypercalciuria, decreased glomerular filtration or a history of nephrolithiasis should be prescribed with caution and with monitoring of urinary calcium content.

A lot of drinking is recommended to reduce the risk of nephrolithiasis.

Contraindications

Hypersensitivity to the drug components, hypercalcemia (calcium concentration should not exceed 12 mg % = 6 mEq/L), hypercalciuria, nephrourolithiasis (calcium), sarcoidosis, intoxication with cardiac glycosides (risk of arrhythmias), severe renal failure, tendency to thrombosis. Children under 5 years old.

With caution:

Dehydration, electrolyte disorders (risk of hypercalcemia), diarrhea, malabsorption syndrome, mild hypercalciuria, moderate chronic renal failure, chronic heart failure, common atherosclerosis, hypercoagulation, chronic gastrointestinal tract disease, calcium nephrourolithiasis in history.

Side effects

Allergic reactions, constipation, gastrointestinal mucosal irritation, nausea, vomiting, diarrhea, upper abdominal pain.

Overdose

Symptoms: hypercalcemia.
Treatment: for its elimination administer – 5-10 IU/kg/day of calcitonin (diluted in 0.5 L of 0.9% sodium chloride solution). The duration of administration is 6 h.

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Pregnancy use

Pregnant women taking calcium preparations together with vitamin D are more likely to develop hypercalcemia.

In recommended doses, taking calcium preparations does not cause any adverse effects on the fetus; it is safe to use even while breastfeeding.

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Similarities

Calcium gluconate, Calcium gluconate Renewal, Calcium gluconate-SOLOPHARM