Calcium chloride, 100 mg/ml 10 ml 10 pcs

Calcium chloride is a calcium preparation, it replenishes the calcium deficiency necessary for the process of transmission of nerve impulses, contraction of skeletal and smooth muscles, myocardial activity, formation of bone tissue, blood clotting.

It reduces cell and vascular wall permeability, prevents the development of inflammatory reactions, increases resistance of the body to infections and may significantly increase phagocytosis (phagocytosis, which decreases after taking sodium chloride, increases after taking calcium preparations).

In intravenous administration it stimulates the symiatic department of the autonomic nervous system, increases the release of epinephrine by the adrenal glands, has a moderate diuretic effect.

Pharmacokinetics
In plasma about 45% is complexed with proteins. About 20% is excreted by the kidneys, the remaining amount (80%) is removed with the contents of the intestine.

Indications

• bleeding of various etiology and localization (pulmonary, gastrointestinal, nasal, uterine, etc.).
• allergic diseases (serum sickness, urticaria, febrile syndrome, itching, Quincke’s edema);
• dystrophic alimentary edema, spasmophilia;
• hypoparathyroidism,
• high vascular permeability (hemorrhagic vasculitis, radiation sickness),
• lack of labor,
• pain from magnesium salts, oxalic and fluoric acids: paroxysmal myoplegia (hyperkalemic form).

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Composition

1 ml of solution for intravenous injection contains:

the active ingredient:

calcium chloride 100 mg,

excipient:

water for injection.

How to take, the dosage

Intravenously, slowly (6-8 drops/minute), 5-15 ml of 10% solution, diluted before injection in 100-200 ml of 0.9% NaCl solution or 5% dextrose solution.

Interaction

When combined with thiazide diuretics may increase hypercalcemia, decrease the effect of calcitonin in hypercalcemia, decrease the bioavailability of phenytoin.

Special Instructions

It should not be administered subcutaneously or intramuscularly, tissue necrosis is possible (high concentrations of calcium chloride starting from 5% cause severe irritation of the vascular wall).
During intravenous administration of calcium chloride a feeling of heat first in the mouth and then – throughout the body (previously used to determine blood flow rate – time between its introduction into the vein and the occurrence of a feeling of heat).

Contraindications

• Hypersensitivity,
• hypercalcemia,
• atherosclerosis,
• susceptibility to thrombosis.